A process for production of a meat product said process comprising the culturing in vitro of animal cells in medium free of hazardous substances for humans on an industrial scale thereby providing three dimensional animal muscle tissue suited for human and/or animal consumption, optionally followed by further processing steps of the cell culture to a finished food product analogous to known processes for meat comprising food products without requiring deboning, removal of offal and/or tendon and
Cultivated Meat Library
1999
1999-06-24
WIPO
1999031222:A1
1997-12-18
World Patent
World Intellectual Property Organization
PC:T/NL1997/000710
2021-11-12
2025-01-17
Vein J
Jon Vein
Method for producing tissue engineered meat for consumption
A non-human tissue engineered meat product and a method for producing such meat product are disclosed. The meat product comprises muscle cells that are grown ex vivo and is used for food consumption. The muscle cells may be grown and attached to a support structure and may be derived from any non-human cells. The meat product may also comprise other cells such as fat cells or cartilage cells, or both, that are grown ex vivo together with the muscle cells.
Cultivated Meat Library
2005
2005-01-13
USPTO
20050010965:A1
2001-11-16
US Patent
United States Patent and Trademark Office
US:09/991544
2021-07-23
2025-01-17
Van Eelen WF
Willem Frederik Van Eelen
Industrial production of meat using cell culture methods
Provided are engineered meat products formed as a plurality of at least partially fused layers, wherein each layer comprises at least partially fused multicellular bodies comprising non-human myocytes and wherein the engineered meat is comestible. Also provided are multicellular bodies comprising a plurality of non-human myocytes that are adhered and/or cohered to one another; wherein the multicellular bodies are arranged adjacently on a nutrient-permeable support substrate and maintained in cul
Cultivated Meat Library
2014
2014-04-03
USPTO
20140093618:A1
2013-11-27
US Patent
United States Patent and Trademark Office
US:14/092801
2021-11-12
2025-01-17
Hasson A,Yirme G,Lavon N,Geffen-Shalev C,Molakandov K
The present invention discloses methods for large scale generation of stem cells. The present invention is directed to compositions and methods for cultivating stem cells, in large-scale culture.
Cultivated Meat Library
2015
2015-01-22
WIPO
2015008275:A1
2014-07-10
World Patent
World Intellectual Property Organization
PC:T/IL2014/050622
2021-07-23
2021-11-02
Genovese NJ,Michael Roberts R,BP
Memphis Meats Inc
Method for scalable skeletal muscle lineage specification and cultivation
The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
Cultivated Meat Library
2016
2016-08-11
USPTO
20160227830:A1
2016-04-20
US Patent
United States Patent and Trademark Office
US:15/134252
2021-07-23
2025-01-17
Marga FS
MODERN MEADOW Inc
Dried food products formed from cultured muscle cells
Dehydrated, edible, high-protein food products formed of cultured muscle cells that are combined (e.g., mixed) with a hydrogel (e.g., a plant-derived polysaccharide) are described. These food products may be formed into a chip (e.g., snack chip), that has a protein content of greater than 50%. One or more flavorants may also be included.
Cultivated Meat Library
2016
2016-08-11
USPTO
20160227831:A1
2016-04-07
US Patent
United States Patent and Trademark Office
US:15/093618
2021-07-23
2025-01-17
Genovese N,Desmet DN,Schulze E
Memphis Meats, Inc.
Methods for extending the replicative capacity of somatic cells during an ex vivo cultivation process
A product and process for extending the replicative capacity of metazoan somatic cells using targeted genetic amendments to abrogate inhibition of cell-cycle progression during replicative senescence and derive clonal cell lines for scalable applications and industrial production of metazoan cell biomass. An insertion or deletion mutation using guide RNAs targeting the first exon of the transcript encoding each protein is created using CRISPR/Cas9. Targeted amendments result in inactivation of p
Cultivated Meat Library
Bos taurus
Gallus gallus
2017
2017-07-20
WIPO
2017124100:A1
2017-01-17
World Patent
World Intellectual Property Organization
PC:T/US2017/013782
2021-07-23
2025-01-17
Hanyu Y,Kawashima I
Growth induction system, growth induction control device, growth induction control method, and growth induction control program
https://patents.google.com/patent/JP6111510B1/en
Patent
Cultivated
Meat
Cell culture media
Bioprocess design
In order to induce growth while suppressing the cost of adding cytokines at each growth stage, the first culture tank for perfusing the culture medium to the growth induction target derived from the living body, the second for perfusing the culture medium to the secretory secreting cytokine In a growth induction system comprising a culture vessel and a growth induction control device comprising a detection unit, a storage unit, and a control unit, a growth induction protocol that defines a growt
Cultivated Meat Library
2017
2017-04-12
Patent
2021-11-12
2025-01-17
Marga FS,Purcell BP,Forgacs G,Forgacs A
Modern Meadow, Inc. (Brooklyn, NY, US)
Edible and animal-product-free microcarriers for engineered meat
http://www.freepatentsonline.com/9752122.html
Patent
Cultivated
Meat
Pectin
Scaffolding
Edible microcarriers, including microcarrier beads, microspheres and microsponges, appropriate for use in a bioreactor to culture cells that may be used to form a comestible engineered meat product. For example, the edible microcarriers described herein may include porous microcarriers that may be used to grow cells (e.g., smooth muscle cells) and may be included with the cells in the final engineered meat product, without requiring modification or removal of the cells from the microcarriers. In
Microcarriers
Cultivated Meat Library
Deep dive: Cultivated meat scaffolding part A
2017
2017-09-05
USPTO
2014-09-15
US Patent
United States Patent and Trademark Office
2021-07-23
2025-01-17
Genovese NJ,Firpo MT,Dambournet D
Memphis Meats, Inc.
Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
Provided herein are methods to increase the culture density and/or thickness of a cellular biomass in a cultivation infrastructure, to improve the culture of cells in the absence of serum in a cultivation infrastructure, and to promote anchorage-independent growth of a cellular biomass in a cultivation infrastructure. The methods comprise inhibiting the HIPPO signaling pathway, for example, by activating YAP1, activating TAZ, and/or inhibiting MOB1, LATS1 kinase, LATS2 kinase, WW45, MST1 kinase,
The present invention is directed to methods, compositions, and systems for the production of fatty acids (FAs). Specifically, the disclosed methods, compositions, and systems incorporate algal cell lysates, providing a cell-free environment that generates high levels of FAs for extended periods of time with the addition of liquid media and a carbon source.
Cultivated Meat Library
2018
2018-12-18
USPTO
10155968
2014-07-29
US Patent
United States Patent and Trademark Office
US:14/909016
2021-11-12
2021-11-24
Nahmias Y
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.
A system for growing cells comprising a bioreactor chamber for growing the cells, a delivery system delivering a perfusion solution to the bioreactor chamber for perfusion of the perfusion solution through the cells, a dialysis system having a dialyzer, a dialysate for performing a dialysis and a filter for reducing ammonia content in said dialysate, and a controller that circulates the perfusion solution through the dialyzer and the dialysate through the filter.
A method of producing a hybrid foodstuff is provided. The method comprises combining a plant-originated substance with an amount of cultured animal cells so as to enhance a meat organoleptic and/or meat nutritional property in the hybrid foodstuff, wherein the animal cells do not form a tissue, and wherein the amount is below 30 % (w/w) of the hybrid foodstuff.
Cultivated Meat Library
2018
2018-10-18
WIPO
2018189738:A1
2018-04-04
World Patent
World Intellectual Property Organization
PC:T/IL2018/050398
2021-07-23
2025-01-17
Vallier L,Kotter M,Pawlowski M,Bertero A,Ortmann D
The present invention relates to a stable method for introducing at least one inducible cassette into a cell, and permitting controllable transcription from within that inducible cassette. The method may be used for any cell type, from any eukaryotic organism, but has a particular application in the introduction of inducible cassettes into pluripotent stem cells, such as animal or human pluripotent stem cells (hPSCs). The inducible cassette is controllably inserted in such a way to ensure that t
Cultivated Meat Library
2018
2018-05-31
WIPO
2018096343:A1
2017-11-24
World Patent
World Intellectual Property Organization
PC:T/GB2017/053531
2021-07-23
2021-11-02
羽生 雄毅,川島 一公
インテグリカルチャー株式会社
Growth guidance system, growth induction controller, growth guidance control method, and the growth induction control program
To induce growth suppressing the cost for each growth stage addition of cytokines, second perfused first culture tank for perfusion of the culture solution in growth induction subject-derived biological, the culture solution secretion body to secrete cytokines fermentor, and the growth induction control device and a control unit and the detection unit and the storage unit, in the growth induction system having a, stores the growth induction protocol that defines the growth induction procedure, t
Cultivated Meat Library
Deep dive: Cultivated meat cell culture media part B
2018
2018-05-31
JP:WO2017191691:A1
2016-06-13
Patent
JP:2016067599A
2021-07-23
2021-07-30
Ben-Arye T,Levenberg S
Technion Research & Development Foundation Limited
The invention is directed to a method for producing an edible composition, comprising incubating a three-dimensional porous scaffold and a plurality of cell types comprising: myoblasts or progenitor cells thereof, at least one type of extracellular (ECM)-secreting cell and endothelial cells or progenitor cells thereof, and inducing myoblasts differentiation into myotubes.
Cultivated Meat Library
Bos taurus
2019
2019-01-24
WIPO
2019016795:A1
2018-07-15
World Patent
World Intellectual Property Organization
PC:T/IL2018/050776
2021-07-23
2025-01-17
Breemhaar JJ,Post M
Mosa Meat BV
Apparatus and process for production of tissue from cells
Disclosed is an apparatus for the production of tissue from cells. The apparatus comprises an elongate body having at least one circumferential groove and being operable to extend, by close-fitting relationship, centrally through at least one trough. The troughs are extending in a closed path, such that the at least one of the circumferential grooves open into an inner edge of a trough. Also disclosed is a process for production of tissue from cells, via a transitioning intermediate which transi
Cultivated Meat Library
Deep dive: Cultivated meat scaffolding part A
2019
2019-11-07
USPTO
20190338232:A1
2018-06-13
US Patent
United States Patent and Trademark Office
US:16/007943
2021-07-23
2021-07-30
Forgacs G,Gupta N
Fork & Goode, Inc
LARGE SCALE CELL CULTURE SYSTEM FOR MAKING MEAT AND ASSOCIATED PRODUCTS
Provided is a large-scale cell culture system for producing products without harming animals. Also provided is a method for making meat products using this cell culture system. Further provided is a m
Cultivated Meat Library
Deep dive: Cultivated meat cell culture media part B
2019
2019-12-12
USPTO
20190376026
2018-08-24
US Patent
United States Patent and Trademark Office
16/112171
2021-07-23
2025-01-17
Genovese NJ,Schulze EN,Desmet DN
Memphis Meats, Inc.
Compositions and methods for increasing the efficiency of cell cultures used for food production
Provided herein are compositions and methods to make and use engineered cells, for the purpose of increasing the cell density of a culture comprising metazoan cells and for the production of a cultured edible product.
Cultivated Meat Library
Deep dive: Cultivated meat bioprocess design
2019
2019-01-17
WIPO
2019014652:A1
2018-07-13
World Patent
World Intellectual Property Organization
PC:T/US2018/042187
2021-07-23
2025-01-17
Bayer E,McIntyre G,Mueller P,O'Brien M,Schaak D,Winiski J,Carlton A
Ecovative Design LLC
Methods of Generating Mycelial Scaffolds and Applications Thereof
Several methods are described for generating mycelial scaffolds for use several technologies. In one embodiment, a mycelial scaffold is generated using a perfusion bioreactor system for cell-based meat technologies. In another embodiment, a mycelial scaffold is prepared for biomedical applications. The mycelial scaffolds may be generated from a liquid medium or from a solid substrate.
Systems and methods for producing cell cultured food products. The cultured food products include sushi-grade fish meat, fish surimi, foie gras, and other food types. Various cell types are utilized to produce the food products and can include muscle, fat, and/or liver cells. The cultured food products are grown in pathogen-free culture conditions without exposure to toxins and other undesirable chemicals.
Cultivated Meat Library
2020
2020-05-07
USPTO
20200140821
2018-06-07
US Patent
United States Patent and Trademark Office
16/620326
2021-07-23
2025-01-17
Johnson JK,Ohst D
NANOFIBER SOLUTIONS, LLC
ELECTROSPUN POLYMER FIBERS FOR CULTURED MEAT PRODUCTION
A cultured meat product may comprise a scaffold comprising an electro spun polymer fiber, and a population of cells. The cultured meat product may have a thickness from about 100 μm to about 500 mm. A
Cultivated Meat Library
2020
2020-08-06
USPTO
20200245658
2020-02-03
US Patent
United States Patent and Trademark Office
16/780187
2021-07-23
2025-01-17
Nahmias Y
Yissum Research Development Company of Hebrew University of Jerusalem
A system for growing cells comprising a bioreactor chamber for growing the cells , a delivery system delivering a perfu sion solution to the bioreactor chamber for perfusion of the perfusion solution through the cells , a dialysis system having a dialyzer , a dialysate for performing a dialysis and a filter for reducing ammonia content in said dialysate , and a controller that circulates the perfusion solution through the dialyzer and the dialysate through the filter .
Cultivated Meat Library
2020
2020
16/316,667
2016
Patent
2021-11-12
2025-01-17
Maiorella BL
Structured "meat" processes and products from cells grown in suspension culture
The present disclosure is directed to methods for the formation and production of renewable muscle and/or fat primary cell lines, immortalized cell lines, and stem cell lines from shrimp, prawn, crab, crayfish, and/or lobster species and the cell lines themselves as well as human and animal consumable meat products produced therefrom.
Cultivated Meat Library
2020
2020-07-23
WIPO
2020149791:A1
2020-01-13
World Patent
World Intellectual Property Organization
PC:T/SG2020/050016
2022-01-06
2025-01-17
Tsuruwaka Y,Ogawa T,Hatada Y
Japan Agency for Marine Earth Science and Technology
Cell line derived from thread-sail filefish (stephanolepis cirrhifer)
The first object of the present invention is to provide an immortalized cell line derived from a thread-sail filefish. The first object of the present invention can be solved by a cell line or a passage strain thereof derived from a living body part of a fish of the family Monacanthidae, wherein the cell line or the passage strain thereof is capable of being subcultured substantially without limitations. The second object of the present invention is to provide a pluripotent stem cell derived fro
The invention is directed to a modified polysaccharide hydrogel, comprising a low molecular weight alginate with a specific M/G ratio. The modified polysaccharide is modified with a specific peptide, preferably comprising a cell-adhesion peptide. The modified polysaccharide hydrogel may be used as a hydrogel for the growth of cultured meat preferably as a sacrificial biopolymer.
Cultivated Meat Library
2021
8/12/21
WIPO
2021158105:A1
2/3/21
World Patent
World Intellectual Property Organization
PC:T/NL2021/050068
2022-08-26
2025-01-17
Tandikul N,Genovese NJ
Upside Foods Inc
Systems and methods for cultivating tissue on porous substrates
Described herein are novel systems and methods for biomanufacturing, such as tissue cultivation. In some variations the systems and methods may comprise at least one porous substrate.
Disclosed herein are systems, devices, and methods for flowing fluid for radially expanded particle distribution within a laminar flow. In some variations, a system for cultivating tissue may comprise a bioreactor comprising an inlet, a substrate arranged in the bioreactor, and a diffusion module configured to transfer fluid from the inlet to the substrate. The diffusion module may comprise a porous material having at least one tortuous conduit extending between a first surface of the porous mat
Cultivated Meat Library
2022
6/23/22
USPTO
20220195368:A1
12/21/20
US Patent
United States Patent and Trademark Office
US:17/129662
2022-08-26
2025-01-17
Cruz H,Flack JE,Furquim C,Klevernic I,Melzener L,Messmer T,Van Essen A
Mosa Meat B.V.
Serum-free medium for differentiation of a progenitor cell
The invention relates inter alia to a method for differentiating a muscle progenitor cell, comprising the step of: - culturing a muscle progenitor cell in a serum-free medium for differentiating a muscle progenitor cell, wherein said serum-free medium comprises - at least one differentiation inducer selected from the group consisting of a lysophosphatidic acid receptor 1 (LPAR1) agonist, a lysophosphatidic acid receptor 3 (LPAR3) agonist, an oxytocin receptor (OXTR) agonist, a glucagon receptor
Cultivated Meat Library
2022
6/2/22
WIPO
2022114955:A1
11/25/21
World Patent
World Intellectual Property Organization
PC:T/NL2021/050718
2022-08-26
2025-01-17
Juarez MV
Biotech Foods SL
Bioreactor and method for the production of adherent cell cultures employing said bioreactor
Bioreactor and production process of adherent cell cultures that uses the bioreactor. The bioreactor includes a recipient with a cover, and further includes internally a bracket from which protrudes at least one tray that supports a three-dimensional polymer-based element mounted on it, such that when the bioreactor is filled with a culture medium the at least one tray and the three-dimensional polymer-based element are surrounded by the culture medium.The process includes the following steps:th
Cultivated Meat Library
2022
6/9/22
USPTO
20220177823:A1
1/4/19
US Patent
United States Patent and Trademark Office
US:17/420274
2022-08-26
2025-01-17
Lavon N,Levanon SS,Nadav TAL
Aleph Farms Ltd.
A multi-scaffold system for large scale cultivation of cells
The present invention is in the field of large-scale production of cultured cells, providing systems comprising a plurality of scaffolds arranged optionally in a multi-layer configuration and methods of use thereof for production of cells and/or tissue cultures for a variety of uses, including the production of cultured food products, particularly cultured meat.
Cultivated Meat Library
2022
5/12/22
WIPO
2022097139:A1
11/3/21
World Patent
World Intellectual Property Organization
PC:T/IL2021/051302
2022-08-26
2025-01-17
Weissenbach JL,Sylvia R,von der Brelie A,Brandl M,Fesenfeld M
Merck Patent Gmbh
Process system for bioreactor-based clean meat production
The present invention is for a closed environment process for the growth and differentiation of cells and the culturing of cells to confluency for the production of tissue. The tissue may be a clean meat product.
Cultivated Meat Library
2022
2/24/22
WIPO
2022038241:A1
8/19/21
World Patent
World Intellectual Property Organization
PC:T/EP2021/073079
2022-08-26
2025-01-17
Weissenbach JL,Sylvia R,von der Brelie A,Brandl M,Fesenfeld M
Merck Patent Gmbh
Consumable tissue-like structure generated with muscle cells grown on edible hollow fibers
The present invention is directed toward edible hollow fibers and cartridges and bioreactors comprising the hollow fibers of the present invention, as well as, methods of production of structured clean meat products produced with the hollow fibers, cartridges and bioreactors of the present invention and the structured clean meat products produced by said methods. The macroscopic structure of structured clean meat grown on edible hollow fibers will result in a unique final structure. This final s
Cultivated Meat Library
2022
2/24/22
WIPO
2022038240:A2
8/19/21
World Patent
World Intellectual Property Organization
PC:T/EP2021/073078
2022-08-26
2025-01-17
Mueller-Auffermann K
Upside Foods Inc
Filter cake-based systems and methods for the cultivation of cells and cell biomass
Provided herein are filter cake-based systems and methods for cultivating cells and cell biomass therefrom. Provided herein is a system for cultivating cells and cell biomass comprising a filter chamber comprising at least one inlet and at least one outlet, at least one filter support located within the filter chamber, and a filter cake located on the filter support, wherein the filter cake comprises at least one filter aid and a plurality of cells. Provided herein is a method for optimizing the
Cultivated Meat Library
2022
5/3/22
USPTO
11319520
9/21/21
US Patent
United States Patent and Trademark Office
US:17/481176
2022-08-26
2025-01-17
Lavon N,Molotski N,Zehorai E,Glick Y,Fireberg KT
Aleph Farms Ltd.
Cell-free animal collagen, methods of production and uses thereof
The present invention relates to the field of use of animal cells for producing products containing animal-derived materials in a sustainable manner, preserving natural resources and promoting animal welfare, particularly for production of cell-free collagen and use thereof for forming textile, particularly leather-like textile, food products, particularly cultured meat, cosmetic products, and medical uses.
Cultivated Meat Library
2022
3/3/22
WIPO
2022043994:A1
8/22/21
World Patent
World Intellectual Property Organization
PC:T/IL2021/051026
2022-08-26
2025-01-17
Li M,Park N,Santo VE
Good Meat, Inc.
Extrudate food compositions comprising cultivated animal cells and methods of production thereof
Provided herein are extruded food products comprising cultivated animal cells and a plant protein. Also provided are methods for preparing extruded food products.
The present invention relates to compositions and methods for mass production of pluripotent stem cells derived from non-human-animal, particularly in a form of aggregates suitable for a variety of uses, particularly to mass production of aggregates of bovine-derived pluripotent stem cells for use in cell grown meat cultures and in production of cell based meat products.
Cultivated Meat Library
2022
7/14/22
USPTO
20220220439:A1
5/14/20
US Patent
United States Patent and Trademark Office
US:17/610485
2022-08-26
2025-01-17
Santo VE,Nguyen CM,Haque MA,Bignone P
Good Meat Inc
Food products comprising cultivated bovine cells and methods thereof
Provided herein are bovine cells that are adapted to grow in growth medium that contains low-serum or no serum and methods thereof. Also provided are food products made from bovine cells cultivated in vitro and methods for harvesting the cells.
Cultivated Meat Library
2022
6/16/22
USPTO
20220183316:A1
12/15/21
US Patent
United States Patent and Trademark Office
US:17/551983
2022-08-26
2025-01-17
Johnson KL,Benton PR,Copeland CG,Dhadwar SS,Firpo MT,Gibbons ME,Hsu SK,Sierra R,Kayser KJ
Upside Foods Inc
Nutrient media for the production of slaughter-free meat
The present disclosure provides methods and systems for the large-scale generation of differentiated stem cells. The present disclosure is also directed to systems and methods for expanding and differentiating stem cells in large-scale culture using a bioreactor chamber.
Cultivated Meat Library
2021
12/16/21
WIPO
2021250407:A1
6/9/21
World Patent
World Intellectual Property Organization
PC:T/GB2021/051437
2022-08-26
2025-01-17
Vila M,Lull T
Biotech Foods S.L.
Process and device for production of cultured meat
The present invention relates to a process for the production of in vitro engineered tissues, also known in the art as cultured meat, cultivated meat, cell based meat, cellular meat and/or clean meat, and a device for the production of the same. The process comprises the steps of: loading sterilizable 3D scaffolds into a seeding chamber; sterilizing the scaffolds in the seeding chamber; seeding the scaffolds by loading a first volume of culture medium into the seeding chamber, wherein the first
Cultivated Meat Library
2021
12/16/21
WIPO
2021250292:A1
6/12/20
World Patent
World Intellectual Property Organization
PC:T/ES2020/070387
2022-08-26
2025-01-17
Vila M,Cortizo D
Biotech Foods S.L.
Edible and sterilizable porous 3d scaffold and uses thereof
The present invention relates to edible and sterilizable macroporous three-dimensional (3D) tissue engineering scaffolds comprising a network of cross-linked biocompatible polymer, preferably a natural polymer. Moreover, the scaffold of the invention further comprises additives and living cells which adhere and proliferate, colonizing the entire surface of the scaffold and giving rise to a raw material for the later formation of tissue with a high nutritive content and/or cultured meat, that may
Cultivated Meat Library
2021
12/16/21
WIPO
2021250291:A1
6/12/20
World Patent
World Intellectual Property Organization
PC:T/ES2020/070386
2022-08-26
2025-01-17
Vila M,Cortizo D
Biotech Foods S.L.
Method for the synthesis of an edible and sterilizable porous 3d scaffold suitable for use in the large-scale production of cultured meat
The present invention relates to a method for the large-scale synthesis of an edible and hot steam sterilizable macroporous three-dimensional (3D) scaffold which comprises biocompatible polymers with interconnected pores as a support material for adherent cell growth, proliferation and differentiation, which may be used to obtain tissue with nutritive content and/or cultured meat. These scaffolds are suitable for supporting cell tissue growth for biomedical or food applications.
Cultivated Meat Library
2021
12/16/21
WIPO
2021250290:A1
6/12/20
World Patent
World Intellectual Property Organization
PC:T/ES2020/070385
2022-08-26
2025-01-17
Juarez MV
Biotech Foods SL
Bioreactor and method for the production of adherent cell cultures employing said bioreactor
Bioreactor and production process of adherent cell cultures that uses the bioreactor. The bioreactor (1) comprises a recipient (2) with a cover (3), and further comprises internally a bracket (4) from which protrudes at least one tray (5) that supports a three-dimensional polymer-based element (6) mounted on it, such that when the bioreactor (1) is filled with a culture medium the at least one tray (5) and the three-dimensional polymer-based element (6) are surrounded by the culture medium.The p
The disclosure relates to print heads for use in the bioprinting of biostructures having predetermined two (2D)- and/or three dimensional (3D) pattern of cells. Specifically, the disclosure relates to print heads operable in a bioprinting systems for the fabrication of edible biostructures using drop-on-demand.
The disclosure relates to methods, systems and compositions for physically manipulating a muscle tissue culture either mechanically, or manually, or both. Specifically, the disclosure relates to systems and methods of physically manipulating, either mechanically or manually, a resilient container of bioprinted tissue culture having non-random three dimensional cell structure by elongation, compression, torque and shear of the tissue culture.
Cultivated Meat Library
2021
3/25/21
WIPO
2021055996:A1
9/22/20
World Patent
World Intellectual Property Organization
PC:T/US2020/052063
2022-08-26
2025-01-17
Fima S,Idan GAL
Meatech 3D, Ltd.
Cultured edible meat fabrication using bio-printing
The disclosure relates to methods, systems and compositions for use in the bio printing of biostructures having predetermined two (2D)- and/or three dimensional (3D) pattern of cells Specifically, the disclosure relates to methods and compositions implementable in a computerized bio-printing systems for the fabrication of edible bio structures using drop-on-demand, having a predetermined three dimensional structure that can be assembled from 2D patterns with cells and extracellular material (ECM
Cultivated Meat Library
2021
1/14/21
WIPO
2021007359:A1
7/8/20
World Patent
World Intellectual Property Organization
PC:T/US2020/041265
2022-08-26
2025-01-17
Ling KY,Sriram S
Shiok Meats Pte Ltd
Isolation and cultivation of muscle and fat cells from crustaceans
The present disclosure is directed to methods for the formation and production of renewable muscle and/or fat primary cell lines, immortalized cell lines, and stem cell lines from shrimp, prawn, crab, crayfish, and/or lobster species and the cell lines themselves as well as human and animal consumable meat products produced therefrom.
Cultivated Meat Library
2021
9/9/21
AU:2020209356:A1
1/13/20
Patent
AU:2020209356A
2022-08-26
2025-01-17
Chin PS,Chan KY,Poon CH
Avant Meats Co Ltd
Cell hydrolysate composition from cultivated cells and applications thereof
A cell hydrolysate composition, the composition comprising substantially all protein polypeptides and/or polypeptide fragments derived substantially from all the proteins in a cell from an in vitro cell culture.
Cultivated Meat Library
2021
8/12/21
USPTO
20210246480:A1
4/28/21
US Patent
United States Patent and Trademark Office
US:17/243493
2022-08-26
2025-01-17
Chin PS,Chan KY,Li CW
Avant Meats Company Limited
System for producing cultivated meats, tissues and associated products from cells
A cell culture system that enhances cell production and reduces the cost of growing cell culture. The system maintains an optimal culture condition by stabilizing the level of nutrients and/or maintaining a minimum level of growth inhibitors in a culture medium. The system comprises a cell culture unit configured to hold at least one type of cell; a fresh medium unit configured to supply and receive the first fluid to the cell culture unit; a waste removal unit configured to supply and receive a
Cultivated Meat Library
2021
6/10/21
WIPO
2021111270:A1
11/30/20
World Patent
World Intellectual Property Organization
PC:T/IB2020/061257
2022-08-26
2025-01-17
네타 라본,일로나 코렌
High-quality cultured meat, composition and method for producing same
The present invention relates to the field of cultured meat, also called clean meat or cell-based meat, in particular to a cell culture for producing cultured meat having sensory properties (color, taste and aroma) at least similar to whole animal-derived meat and improved nutritional value. The present invention also provides a cell culture and a culture medium for producing high-quality cultured meat.
The present invention relates to compositions and methods for mass production of pluripotent stem cells derived from non-human-animal, particularly in a form of aggregates suitable for a variety of uses, particularly to mass production of aggregates of bovine-derived pluripotent stem cells for use in cell grown meat cultures and in production of cell based meat products.
The invention is in the field of cultured meat. In particular the invention is related to a method for aseptic packaging of cultured tissue and a system suitable for this method. The method comprises the steps of producing the cultured tissue, harvesting the cultured tissue, transferring the cultured tissue to a sterile package and sealing the sterile package, wherein all steps are executed under aseptic conditions.
Cultivated Meat Library
2021
8/12/21
WIPO
2021158104:A1
2/3/21
World Patent
World Intellectual Property Organization
PC:T/NL2021/050067
2022-08-26
2025-01-17
Moutsatsou P,Cruz H,Klevernic I,Kolkmann A,Van Essen A
Mosa Meat B.V.
Serum-free medium for culturing a bovine progenitor cell
A method for culturing a bovine progenitor cell, comprising the step of: culturing a bovine progenitor cell in a serum-free medium for culturing a bovine progenitor cell, wherein said serum-free medium comprises - an albumin; and - a fibroblast growth factor (FGF).
Cultivated Meat Library
2021
8/12/21
WIPO
2021158103:A1
2/3/21
World Patent
World Intellectual Property Organization
PC:T/NL2021/050066
2022-08-26
2025-01-17
Genovese NJ
Memphis Meats, Inc.
Use of tead proteins for production of cellular biomass
Provided herein are methods to increase the culture density and/or thickness of a cellular biomass in a cultivation infrastructure, and to promote anchorage-independent growth of a cellular biomass in a cultivation infrastructure. The methods comprise activating a TEAD protein, for example, by increasing cellular expression of the TEAD protein or by increasing cellular expression of a fusion protein comprising a DNA-binding domain (DBD) derived from a TEAD protein and a transcriptional activatio
Cultivated Meat Library
2021
5/14/21
WIPO
2021092587:A1
11/9/20
World Patent
World Intellectual Property Organization
PC:T/US2020/059744
2022-08-26
2025-01-17
Kayser KJ,Rease ML,Juhas ME,Joslin JM,Valeti US,Schulze EN
The present disclosure provides methods and compositions useful for the production of slaughter-free meat products, and the characterizations of the same. The slaughter-free meat products contain several points of distinction when compared to conventional meat procured by harvesting the tissue of a dead animal. Such points of distinction include, but are not limited to, significantly reduced or substantially no: steroid hormones, antibiotics, or microbial contamination; lower fat content; no vas
Cultivated Meat Library
2021
8/5/21
USPTO
20210235733:A1
9/25/20
US Patent
United States Patent and Trademark Office
US:17/033635
2022-08-26
2025-01-17
Leung M,Godbole A,Engelmayr Jr GC,Genovese NJ,Valeti US,Carswell K
Memphis Meats, Inc.
Apparatuses and methods for preparing a comestible meat product
The substrates, systems, and methods described herein relate to textured substrates for preparing a comestible meat product. Substrates and methods are described herein for controlling one or more of growth, adhesion, retention, and/or release of cells (e.g., of a cell sheet) on or from the surface of the substrate. A method of preparing a comestible meat product may include applying a plurality of non-human cells to at least one patterned texture substrate, growing the cells on the patterned te
Cultivated Meat Library
2020
12/3/20
WIPO
2020243324:A1
5/28/20
World Patent
World Intellectual Property Organization
PC:T/US2020/034949
2022-08-26
2025-01-17
Leung M,Warner M,Vanderpol RE,Hsiu TP,Carswell K
Upside Foods Inc
Apparatuses and systems for preparing a meat product
The apparatuses described herein relate to preparation of a meat product. Apparatuses, systems comprising the apparatuses, and methods of making and use the systems and apparatuses are described herein. These are useful for controlling one or more of growth on and separation of a meat product from an enclosed substrate. The apparatuses and systems are configured to receive fluid and grow the meat product and/or separate the meat product from the substrate in a scalable manner.
Systems and methods for producing food products including cultured food products. The cultured food products include sushi-grade fish meat, fish surimi, foie gras, and other food types. Various cell types are utilized to produce the food products and can include muscle, fat, and/or liver cells. The cultured food products are grown in pathogen-free culture conditions without exposure to toxins and other undesirable chemicals. The food products can be processed to provide a desired shape, texture
Cultivated Meat Library
2020
6/18/20
WIPO
2020123876:A1
12/12/19
World Patent
World Intellectual Property Organization
PC:T/US2019/066089
2022-08-26
2025-01-17
Lavon N,Aviv M,Roth Y,Toubia D
Aleph Farms Ltd.
Cultivation systems and methods for large-scale production of cultured food
Systems and methods for producing cultured food products such as cultured meat in a form of meat cut or offal are provided, comprising growing non-human-animal adherent cells on edible scaffold(s) in a cultivation system. The cultivation system typically comprises a plurality of cell culture bioreactors receiving medium at a controlled flow rate adjusted to nourish the non-human-animal adherent cells.
Cultivated Meat Library
2020
11/5/20
WIPO
2020222239:A1
4/30/20
World Patent
World Intellectual Property Organization
PC:T/IL2020/050484
2022-08-26
2025-01-17
Mullen N,Park N,Jones C,Bowman T,Bignone P,Santo VE,Kambam P,Haque A,Amadi IM
Provided herein are food products made in vitro from avian fibroblast cells and methods for harvesting the avian fibroblast cells. Particularly, an in vitro produced chicken product is produced. Also provided herein are methods of their production.
Cultivated Meat Library
2020
12/17/20
USPTO
20200392461:A1
6/12/20
US Patent
United States Patent and Trademark Office
US:16/900719
2022-08-26
2025-01-17
Forgacs G,Marga FS,Norotte C
University of Missouri System
Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same
Structures and methods for tissue engineering include a multicellular body including a plurality of living cells. A plurality of multicellular bodies can be arranged in a pattern and allowed to fuse to form an engineered tissue. The arrangement can include filler bodies including a biocompatible material that resists migration and ingrowth of cells from the multicellular bodies and that is resistant to adherence of cells to it. Three-dimensional constructs can be assembled by printing or otherwi
Provided are engineered meat products formed as a plurality of at least partially fused layers, wherein each layer comprises at least partially fused multicellular bodies comprising non-human myocytes and wherein the engineered meat is comestible. Also provided are multicellular bodies comprising a plurality of non-human myocytes that are adhered and/or cohered to one another; wherein the multicellular bodies are arranged adjacently on a nutrient-permeable support substrate and maintained in cul
Cultivated Meat Library
2013
1/31/13
USPTO
20130029008:A1
7/26/12
US Patent
United States Patent and Trademark Office
US:13/558928
2022-08-26
2025-01-17
Engelmayr, G.C., Fischer, I.E., Bergeron, A., Shahrokhi, S., Paton, W.C., Maciag, V., Radstrom, X.G., Beville, A., Yaman, R.
Mission Barns, Inc
Scalable bioreactor systems and related methods of use
Bioreactors configured to scale-up the production of greater quantities of cells at relatively low cost are provided. These bioreactors may be utilized in the production of large-scale quantities of cell-based meat and cell-based fat. The bioreactors may be reusable and may have a high surface area-to-volume ratio for adherent cell expansion. The bioreactors may be capable of yielding a large number of adherent cells per bioreactor unit.
Cultivated Meat Library
2021
10/14/21
WIPO
2021207293A1
4/6/21
World Patent
World Intellectual Property Organization
2022-08-26
2025-01-17
Leung M,Benton PR,Copeland CG,Hsu SK,Johnson KL
Upside Foods Inc
Systems, devices, and methods for sterilizing bioreactors and culture media
Disclosed herein are systems, devices, and methods for sterilization. In some variations, a method of sterilizing a bioreactor system may comprise circulating a sterilant in a bioreactor and an enclosed vessel in fluidic communication with the bioreactor. The enclosed vessel may comprise cell culture media. The sterilant may be circulated for a dwell time sufficient to sterilize at least one of the bioreactor, the vessel, and the cell culture media.
Cultivated Meat Library
2022
2/24/22
USPTO
20220056394:A1
8/18/20
US Patent
United States Patent and Trademark Office
US:16/996567
2022-08-26
2025-01-17
Teglia L,Sharma VL,Handlin Jr DL,Kleiman I,Varadaraju H
Modern Meadow Inc
Layered collagen materials and methods of making the same
The present disclosure provides layered collagen materials comprising one or more collagen/polymer matrix layers. The collagen/polymer matrix layer(s) are formed of a collagen blended with one or more polymers. The collagen blended within the polymer(s) can be dissolved within the polymer(s). The one or more collagen/polymer matrix layers can be attached to a substrate layer, for example a fabric layer.
The present invention provides a cell culture management system. The cell culture management system of the present invention comprises: an output data server provided for a first culture device for culturing a first cell; a customer server provided for a second culture device for culturing a second cell; and a cell management server provided for a cell management repository storing the second cell, wherein the output data server, the customer server, and the cell management server are individual
Cultivated Meat Library
2021
2021-08-19
WIPO
2021161397:A1
2020-02-10
World Patent
World Intellectual Property Organization
PC:T/JP2020/005189
2022-08-31
2025-01-17
川岛一公,羽生雄毅,福本景太
Integriculture Inc
Animal cell growth promoter, medium for animal cell culture, and animal cell culture device
The object of the present invention is to provide a novel animal cell growth promoter. Specifically, a culture supernatant of an embryonic membrane of an egg of an avian or reptile is used as an animal cell proliferation promoter. For example, the proliferation of animal cells can be promoted by adding a cell proliferation agent containing, as an active ingredient, a culture supernatant of an embryonic membrane of an egg of birds or reptiles to a culture medium for animal cell culture.
Cultivated Meat Library
2021
2021-06-22
CN:113015789:A
2019-11-07
Patent
CN:201980074375.3A
2022-08-31
2025-01-17
Nahmias Y,Wissotsky G
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.
Methods and devices for filtering cell culture media
The present disclosure provides, in part, a receptacle for filtering a liquid. The receptacle comprises a plurality of hollow fibers extending the length of the receptacle and at least one solid absorbent material occupying a space between the plurality of hollow fibers. Each hollow fiber comprises at least one opening and a lumen defined by the walls thereof, allowing the liquid to flow through. The hollow fiber walls have a porosity profile selective to passage of waste materials contained in
Cultivated Meat Library
2021
2021-08-05
WIPO
2021152536:A1
2021-01-29
World Patent
World Intellectual Property Organization
PC:T/IB2021/050728
2023-01-13
2025-01-17
Khademhosseini A,Hosseini SV,Zamanian B
Constructs for meat cultivation and other applications
The present disclosure provides, in part, a cell culture medium supplement comprising at least one plant protein homologue of a serum protein, a cell culture medium comprising a serum-free base medium and one or more plant based proteins, and methods of growing cells in vitro and of producing cultured meat using the cell culture medium.
Cultivated Meat Library
2021
2021-07-29
WIPO
2021148955:A1
2021-01-20
World Patent
World Intellectual Property Organization
PC:T/IB2021/050413
2023-01-13
2025-01-17
Nahmias Y,Halaf G,Shidlovsky Z,Wissotsky G
Future Meat Technologies Ltd.
Systems and methods for recycling cell culture medium
The present disclosure provides, in part, a system for recycling a cell culture medium. Also provided is a method for recycling a cell culture medium. Such system and method can be used to produce culture meat or remove waste products from a patient's blood.
Cultivated Meat Library
2022
2022-11-17
WIPO
2022238867:A1
2022-05-09
World Patent
World Intellectual Property Organization
PC:T/IB2022/054287
2023-09-07
2023-10-06
Pereira-Taveres AJ,Engelmayr Jr GC,Helgason I
Vitrolabs Inc United Kingdom
Scalable bioreactor systems and methods for tissue engineering
Disclosed herein are scalable, modular bioreactor systems for efficient preparation of cell-based tissues. Also disclosed herein are methods, compositions, and apparatuses for preparing scaffolds.
An apparatus for biologically culturing meat, comprising a culture medium regulation tank (1), a cell proliferation tank (2), a muscle separation tank (3), a compression shaping apparatus (4) and a control system, wherein the control system comprises a culture medium regulation and control system (51) for controlling the culture medium regulation tank (1), a cell proliferation control system (52) for controlling the cell proliferation tank (2), and a muscle collection and shaping control system
A system and method for producing a composition comprising plant derived polypeptides, and at least one enzyme capable of crosslinking said plant derived polypeptides. The composition comprising a porous plant protein matrix comprising crosslinked plant derived polypeptides, and at least one enzyme capable of catalyzing amino acid oxidation and/or at least one enzyme capable of forming peptide bonds between amino acid residues, wherein the matrix is capable of forming a hydrogel when hydrated.
Cultivated Meat Library
2023
2023-03-09
WIPO
2023031914:A1
2022-08-28
World Patent
World Intellectual Property Organization
PC:T/IL2022/050932
2023-09-07
2023-10-06
Savir I,Peretz YL,Halevy T,Halimi R
Supermeat The Essence Of Meat Ltd.
Methods for preparing a food ingredient and compositions produced thereby
A method of producing a food ingredient is provided. The method comprising: (a) providing stem cells; and (b) culturing the stem cells in the presence of an affective amount of fatty acids or precursor thereof selected to reach an intracellular fatty acid profile of an edible species of interest which is not of the stem cells, so at to result in a food ingredient having a lipid organoleptic property of the edible species.
Cultivated Meat Library
2023
2023-04-27
WIPO
2023067595:A1
2022-10-18
World Patent
World Intellectual Property Organization
PC:T/IL2022/051101
2023-09-07
2023-10-06
王守伟,李石磊,李莹莹,刘文婷,李雨爽
中国肉类食品综合研究中心
Special culture apparatus for 3d biological tissue, and method for preparing block-shaped cultured meat
A special culture apparatus for 3D biological tissue, and a method for preparing block-shaped cultured meat. The special culture apparatus for 3D biological tissue comprises: a 3D biological tissue culture tank for having 3D biological tissue placed therein, and a liquid storage tank for containing a culture medium, wherein the 3D biological tissue culture tank is connected to the liquid storage tank by means of a pipeline to form a circulation loop for the culture medium to circularly flow; and
Cultivated Meat Library
2022
2022-04-07
WIPO
2022068029:A1
2020-11-27
World Patent
World Intellectual Property Organization
PC:T/CN2020/132217
2023-09-07
2025-01-17
Nahmias Y,Ayyash M,Pasitka L
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.
The present disclosure provides, in part, a cell culture medium comprising a serum-free medium and one or more fibroblast growth factor (FGF) activators, a kit comprising the cell culture medium and instructions for use, methods of growing cells in vitro and of producing a cultured meat using the cell culture medium, and a cultured meat so produced.
Cultivated Meat Library
2021
2021-07-29
WIPO
2021148960:A1
2021-01-20
World Patent
World Intellectual Property Organization
PC:T/IB2021/050419
2023-09-07
2023-10-06
Tzahor E,Porat-Avinoam O,Eigler-Hirsh TM
Yeda Research And Development Co. Ltd.
Method for inducing hypertrophic muscle fibers for industrial meat production
A method of inducing multinucleated myotube formation is provided. The method comprising contacting myogenic precursor cells from a farmed animal with an Extracellular Regulated Signaling Kinase (ERK1/2) inhibitor and/or an upregulator of intracellular Ca 2+ and/or RXR/RAR agonists, enhancing fusion and myogenic maturation.
Cultivated Meat Library
2022
2022-11-10
WIPO
2022234586:A1
2022-05-05
World Patent
World Intellectual Property Organization
PC:T/IL2022/050474
2023-09-07
2025-01-17
关欣,堵国成,严其洋,周景文,陈坚
Jiangnan University
Serum-free myogenic differentiation medium containing natural compound and application thereof
The invention discloses a serum-free myogenic differentiation medium containing a natural compound and application thereof, belonging to the technical field of animal cell culture and cell culture meat. The invention characterizes the influence of an improved serum-free culture medium on the differentiation state of myogenic cells by the apparent observation of the differentiation state of the cells, the immunofluorescence staining of a muscle specific protein MyHC, and the analysis of the diffe
Cultivated Meat Library
2022
2022-07-15
CN:114752554:A
2022-01-14
Patent
CN:202210041678.9A
2023-09-07
2023-10-06
Shujian ONG
Ants Innovate Pte. Ltd.
Scalable methods for manufacturing alternative meat cuts
This invention relates to scalable methods for the production of artificial meat products that mimic the appearance, texture, and mouthfeel (ATM) of natural meat cuts. These methods involve providing multiple building blocks of edible protein, such as grooved sheets, fibrils or fibres of edible protein, and combining the building blocks with an edible binder to produce the artificial meat product. Methods are provided along with apparatus for performing the methods and artificial meat products p
Cultivated Meat Library
2022
2022-09-15
WIPO
2022189505:A1
2022-03-09
World Patent
World Intellectual Property Organization
PC:T/EP2022/056033
2023-09-07
2023-10-06
Kaplan DL,Stout A,Yuen Jr J,Rubio N
Trustees Of Tufts College
Ectopic cellular growth factor expression for low-cost production of cell-cultured foods
The present disclosure relates to cultured tissue, methods for production of self-sufficient modified cells for producing cultured tissue. Further, the disclosure provides methods of generating cultured meat products without exogenous addition of growth hormones.
Cultivated Meat Library
2022
2022-05-19
WIPO
2022104373:A1
2021-11-12
World Patent
World Intellectual Property Organization
PC:T/US2021/072383
2023-09-07
2025-01-17
박병철,박태섭
서울대학교 산학협력단
Myoblast cell established from chicken pectoralis major and method for screening physiological active substance using the same
The present invention relates to a method for screening a physiological active substance using a myoblast cell line established from chicken pectoralis major. The myoblast cell line established from chicken pectoralis major was treated with extracts of angelica and angelica by-products as physiologically active candidates, and then gene expression levels thereof were compared with that of untreated control myoblast cell lines. As a result, the angelica and angelica by-product extracts have been
Cultivated Meat Library
2020
2020-11-16
KR:102179463:B1
2019-12-06
Patent
KR:1020190161483A
2023-09-07
2023-10-06
郭仁朋,刘政,丁世杰,林玲,唐长波
Nanjing Agricultural University
Culture medium for in vitro large-scale culture of meat seed cells and gene operation method
The invention provides an improved culture medium for in vitro amplification culture of meat seed cells and a gene manipulation method. The improved culture medium is added with an activator and an inhibitor targeting a Hippo-YAP pathway, and the activator and the inhibitor can promote muscle stem cell proliferation and maintain sternness gene expression under high-density conditions. The gene operation method refers to the gene operation of knocking down, knocking out, over-expressing and the l
Cultivated Meat Library
2021
2021-12-31
CN:113862225:A
2021-10-08
Patent
CN:202111169385.0A
2023-09-07
2025-01-17
Rease ML,Wicke A
Upside Foods, Inc.
Comestible cell-based meat products comprising dry cell powder and methods of making such products
This disclosure generally describes comestible cell-based food products including a combination of cultured cells and dry cell powder and methods for preparing such cell-based food products. In one or more embodiments, the comestible cell-based food product comprises a mixture of cultured animal cells and dry cultured animal cell powder. For example, the comestible cell-based food product is produced by generating a homogenous mixture of cultured animal cells and dry cultured animal cell powder.
Cultivated Meat Library
2022
2022-12-15
WIPO
2022261647:A1
2022-06-08
World Patent
World Intellectual Property Organization
PC:T/US2022/072825
2023-09-07
2025-01-17
Dhadwar SS,Kayser KJ,Genovese NJ
Upside Foods, Inc.
Generation of cell-based products for consumption that comprise proteins derived from exotic, endangered, and extinct species
The present disclosure relates to methods of preparing cell-based products for consumption that comprise proteins from exotic, endangered, and extinct species, as well as cell-based products for consumption.
Cultivated Meat Library
2022
2022-10-13
WIPO
2022216742:A1
2022-04-05
World Patent
World Intellectual Property Organization
PC:T/US2022/023536
2023-09-07
2025-01-17
Liu R,Warner M,Kang JS,Leung M,Ordonez E,Patel R,Muller-Auffermann K
Upside Foods, Inc.
Fluid dispenser for recovering material from a surface
An assembly for delivering a fluid includes a fluid dispenser connected to a fluid supply conduit. The fluid dispenser includes a fluid outlet positioned along a length of the fluid dispenser. The fluid outlet is configured to deliver the fluid from the fluid supply conduit at a flow rate that varies along the length of the fluid dispenser.
Cultivated Meat Library
2022
2022-12-22
WIPO
2022265640:A1
2021-06-17
World Patent
World Intellectual Property Organization
PC:T/US2021/037786
2023-09-07
2023-10-06
Rowat A,Kawecki NS,Braybrook SA,Norris S
The Regents Of The University Of California
Methods and compositions for cell culture on heterogeneous scaffolds
Embodiments of the invention describe a cultured meat or food product with more desirable flavor and texture, as well as methods and compositions for producing the same. Certain embodiments are directed to methods of producing a stiffer, structured surfaces or scaffolds that mimic the extracellular matrix (ECM) and support the growth of myotubes that are interspersed with a scaffold component supporting fat cells (adipocytes) in vitro .
Cultivated Meat Library
2020
2020-10-29
WIPO
2020219755:A1
2020-04-23
World Patent
World Intellectual Property Organization
PC:T/US2020/029629
2023-09-07
2025-01-17
冯宪超,周光宏,陈琳,陈晓红,李鳞子,陈燕,刘亚平
Northwest A&F University
Method for manufacturing edible pectin chitosan collagen 3D scaffold for cell culture meat
The invention relates to a method for manufacturing an edible pectin/chitosan/collagen 3D scaffold for cell culture meat, and the pectin/chitosan/collagen 3D gel scaffold manufactured by the method can be used for culturing skeletal muscle cells and providing support for manufacturing cell culture meat, belonging to the technical field of future food. The pectin/chitosan/collagen 3D scaffold is prepared by uniformly mixing pectin (high methoxyl pectin and low methoxyl pectin) with a certain conc
The present disclosure relates to cultured adipose tissue. In one embodiment, the cultured adipose tissue is produced by culturing adipose cells in a culture media in vitro, harvesting the adipose cells after a desired amount of adipose cells are produced, and aggregating the harvested adipose cells to provide the cultured adipose tissue. In some embodiments, aggregating the harvested adipose cells comprises mixing the harvested adipose cells with a hydrogel or binder in a three-dimensional (3D)
Cultivated Meat Library
2022
2022-05-19
WIPO
2022104378:A1
2021-11-12
World Patent
World Intellectual Property Organization
PC:T/US2021/072389
2023-09-07
2025-01-17
Bubner P,Daley L,Levesque-Tremblay G
Orbillion Bio, Inc.
Using organoids and/or spheroids to cultivate meat
A method is described herein. The method includes: acquiring cells from a non-human animal source such as a tissue biopsy, stem cells, precursor cells, embryonic cells, bone marrow or any combination thereof after identification of immortalized cell lines, improvement of cell lines, or a spontaneous immortalization event; expanding cells from the non-human animal source in a plate or microfluidics chip to facilitate a formation of spheroids or organoids in a range of approximately 10 µm to appro
Cultivated Meat Library
2022
2022-04-28
WIPO
2022086926:A1
2021-10-19
World Patent
World Intellectual Property Organization
PC:T/US2021/055556
2023-09-07
2025-01-17
Connon CJ,Gouveia R
3D Bio-Tissues Limited
Cell culture medium and supplements for cellular meat production
The present invention provides novel cell culture media and supplements for use in serum- free or reduced-serum cell culture. Corresponding methods and uses are also provided. The novel cell culture media and supplements are particularly beneficial when used during in vitro cell culture of fat cells, muscle cells, or a combination thereof.
The present invention provides a supplement composition and method of preparation thereof for cell culture. The supplement composition comprises natural substances without using any animal based serum. The present invention provides slaughter free, effective and affordable supplement for growth of animal cells that eliminates or minimizes dependency on the fetal bovine serum.
Cultivated Meat Library
2022
2022-06-23
WIPO
2022130162:A1
2021-12-13
World Patent
World Intellectual Property Organization
PC:T/IB2021/061622
2023-09-07
2023-10-06
Max RYE,Fengru LIN,Toor RH,Yong G,Shahid S
Turtletree Labs Pte. Ltd.
Nutrient compositions and methods, kits, and cell compositions for producing the same
Compositions, kits, and methods for preparing nutrient compositions are provided. A nutrient composition can be a food composition such as a dairy composition. A nutrient composition may be produced by an engineered cell composition. Compositions, kits, and methods for preparing engineered cell compositions for producing nutrient compositions are also provided. An engineered cell composition may comprise genetically engineered cells, such as genetically engineered mammary or mammary-like cells.
Cultivated Meat Library
2021
2021-04-08
WIPO
2021067641:A1
2020-10-01
World Patent
World Intellectual Property Organization
PC:T/US2020/053866
2023-09-07
2023-10-06
Goh H,Wu YY,Yong G
Turtletree Labs Pte. Ltd.
Bioreactor systems and methods for culturing cells
The present disclosure relates to apparatus, systems and methods for culturing cells, e.g., mammalian cells, and in particular instances, mammary cells. The present disclosure describes the use of various 3D cell scaffolds, in particular hollow fiber bioreactors, for the cell seeding, proliferation and differentiation of the cells (e.g., mammalian cells such as mammary cells). The use of magnetic mechanisms for moving the cell scaffold relative to the bioreactor vessel is disclosed. In one embod
Cultivated Meat Library
2022
2022-06-02
WIPO
2022115033:A1
2021-11-16
World Patent
World Intellectual Property Organization
PC:T/SG2021/050704
2023-09-07
2023-10-06
Fengru L,Max R,Rabail T,Saher S
Turtletree Labs Pte Ltd
Method of producing milk and related dairy products in the lab using stem cells isolated from different mammals
An apparatus for culturing muscle tissue comprises a chamber extending from a first end to a second end; a first anchor located within the chamber at the first end; a second anchor located within the chamber at the second end; an inlet; and an outlet. The chamber can have an expanding or cylindrical cross-section from each of the first end and the second end to a point between the first end and the second end. The first and second anchors are three-dimensional.
Cultivated Meat Library
2022
2022-09-29
WIPO
2022203513:A1
2022-03-25
World Patent
World Intellectual Property Organization
PC:T/NL2022/050165
2023-09-07
2023-10-06
Nonnenmacher P,Drescher P
Innocent Meat GmbH
Methods to produce defined, spherical, bio-degradable macroporous microcarriers/hydrogels for cellular agriculture
Biocompatible macroporous microcarriers, including microcarrier beads, microspheres, capsules, microsponges, hydrogels and other matrix forms, appropriate for use in a shaking flask or bioreactor to culture cells are described herein that can be used to create an edible structure for consumption or research investigation. Biocompatible, macroporous microcarriers can be dissolved or remain in the final product. Biocompatible macroporous microcarriers are formed by saccharides that are cross-linke
Cultivated Meat Library
2022
2022-12-01
WIPO
2022249076:A1
2022-05-25
World Patent
World Intellectual Property Organization
PC:T/IB2022/054873
2023-09-07
2023-10-06
박길준,김희정,이민수,배준혁,임종영
셀미트주식회사
Scaffold including bio-cellulose for manufacturing cultured meat and preparation method thereof
The present invention relates to a scaffold for manufacturing cultured meat comprising microbial-derived bio-cellulose and a manufacturing method thereof. The scaffold based on microbial-derived bio-cellulose has cell engraftment and a structure similar to that of chicken, beef, or pork, and thus can be used for manufacturing cultured meat.
Disclosed herein are cultured milk product compositions that comprise protein, lipid, and oligosaccharide components at concentrations that mimic and/or are substantially similar to bovine milk. The cultured milk product compositions include one or more milk components produced in vitro and/or ex vivo from cultured bovine mammary cells.
Provided herein are cultured milk products for use as nutritional supplements. Also provided are live cell constructs for producing the cultured milk products and bioreactors for producing the cultured milk products. Secretory IgA compositions and methods of use are also provided.
Cultivated Meat Library
2021
2021-12-02
WIPO
2021242866:A1
2021-05-26
World Patent
World Intellectual Property Organization
PC:T/US2021/034267
2023-09-07
2023-10-06
Benson CA,Madden LR
Bluenalu, Inc.
Cell-cultured food products and related cells, compositions, methods and systems
Provided herein are culture medium, methods and systems to culture cells of an aquatic animal to increase lipid uptake, cell viability and/or cell differentiation in presence of one or more lipids at a concentration of at least 10 μg/ml, and cells obtainable and obtained thereby, related cell biomass and food products. Also provided herein are culture medium, methods and systems to culture cells of a terrestrial animal to increase lipid uptake, cell viability and/or cell differentiation in prese
Cultivated Meat Library
2022
2022-11-24
WIPO
2022221261:A3
2022-04-12
World Patent
World Intellectual Property Organization
PC:T/US2022/024391
2023-09-07
2023-10-06
Fulga V,Bubnic S,Johnston E,Haidun LIU,Pollack J,Currie P,Ebrahimi M
Cultivated seafood muscle cells are produced through a process that first isolates culture initiating cells from tissue using mechanical and enzymatic means and then expanding their number over time in culture. Methods for enhancing yield of seafood muscle cells are used for manufacturing a seafood product.
Meat emulsion products and methods for producing meat emulsion products that have realistic fiber definition. The meat emulsion products comprise a protein, a fat, and a plurality of colors and/or textures. The meat emulsion products further comprise a plurality of linear strands of fiber-like material affording the meat emulsion product a realistic meat-like appearance.
The invention relates to a structured fat system for use in food applications. The invention also relates to the use of a structured fat system for reducing the trans- and saturated fat content of a food product.
The invention provides an isolated thermostable polypeptide possessing FGF2 activity and having at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof, and comprising at least one amino acid substitution R31L and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. Further it discloses a culture medium comprising subjected FGF2 suitable for culturing a human pluripotent stem cells involving both huma
A thermostable polypeptide having the biological activity of FGF18, and containing a sequence with at least 90% sequence identity to the sequence: LYSR TSGKHIQVLG RRISARGEDG DKYAQLLVET DTFGSQVRIK GKETEFYLCM NRKGKLVGKP DGTSKECVFI EKVLENNYTA FMSAKYPGWY VGFTKKGRPR KGPKTRENQP DVHFM (SEQ ID NO. 3) where the amino acids marked in bold and underlined must be preserved. Preferably, the total length of the polypeptide sequence is up to 227 amino acids, more preferably up to 207 amino acids. Said polypept
Cultivated Meat Library
2023
2023-04-05
CZ:309550:B6
2021-06-15
Patent
CZ:2021-303A
2023-09-07
2023-10-06
Chaloupkova R,Stepankova V,Horackova A,Bednar D,Kutalkova K
Enantis SRO
Thermostable fgf10 polypeptide or fragment thereof use thereof
The invention relates to a thermostable FGF10 polypeptide possessing FGF10 activity and having or comprising at least 85% sequence identity to SEQ ID NO:3 that has or comprises an amino acid sequence from Ser69 to Ser208 of SEQ ID NO:1, or to SEQ ID NO:5 that has or comprises an amino acid sequence from Leu40 to Ser208 of SEQ ID NO:1, or the fragments thereof, comprising at least an amino acid substitution L152F. Preferably, any of amino acid substitutions V123I, Q175E, and N181D can be further
Cultivated Meat Library
2023
2023-05-24
EPO
4183796:A1
2021-11-19
European Patent
European Patent Office
EP:21209408.0A
2023-09-07
2023-10-06
Takle S,Sachdeva NS,Srivastava A
Myoworks Pvt. Ltd.
A scaffolding for cultivated meat and a process for making the same
The present invention relates to an edible scaffolding for cultivated meat made of edible mushroom mycelium. Preferably the scaffolding has a polysaccharide backbone that imparts a 3 dimensional structure and mimics the macroscopic shape of natural meat. The present invention also relates to a process for making the edible scaffolding and the structural backbone. The cultivated meat formed by the process of this invention imitates the texture, shape, appeal, nutrient value and taste as that of n
본 발명의 제1 실시예에 따른 인공육 제조 방법은, 살코기의 맛을 구현하는 원료가 가용화된 제1 압출전원료가 형성되는 단계, 상기 제1 압출전원료가 압출되어 압출 방향에 따른 길이를 갖는 적어도 하나의 제1 압출 섬유가 획득되는 단계, 지방의 맛을 구현하는 원료가 가용화된 제2 압출전원료가 형성되는 단계, 상기 제2 압출전원료가 압출되어 압출 방향에 따른 길이를 갖는 적어도 하나의 제2 압출 섬유가 획득되는 단계 및 적어도 하나의 상기 제1 압출 섬유와 적어도 하나의 상기 제2 압출 섬유가 상기 길이 방향을 따라 연결된 인공육이 획득되는 단계를 포함한다.
Cultivated Meat Library
2023
2023-04-20
WIPO
2023063468:A1
2021-11-05
World Patent
World Intellectual Property Organization
PC:T/KR2021/015993
2023-09-07
2023-10-06
최광환,윤지원,이동경,이창규,조철훈,김민수
주식회사 스페이스에프
Buffer solution composition for efficient isolating muscle stem cells
The present invention relates to a buffer composition for isolating muscle stem cells and a method for isolating muscle stem cells from food-producing animals using the buffer composition. The buffer composition for isolating stem cells of the present invention increases muscle stem cell yield by reducing apoptosis when isolating muscle stem cells from food-producing animals, and thus can be used for agricultural biotechnology applications such as cultured meat production.
Cultivated Meat Library
2022
2022-04-28
KR:102391917:B1
2021-08-24
Patent
KR:1020210111592A
2023-09-07
2023-10-06
최광환,윤지원,김민수,이동경,조철훈,이창규
주식회사 스페이스에프
Medium composition for culturing muscle stem cells of domestic animals
The present invention relates to a composition for culturing livestock muscle stem cells, and since the composition for culturing livestock muscle stem cells of the present invention can maintain the proliferative capacity and differentiation capacity of porcine muscle cells in vitro for a long period of time, it is possible to be used for agricultural biotechnology applications such as production of cultured meat. The present invention relates to the composition for culturing livestock muscle s
Cultivated Meat Library
2022
2022-07-29
KR:102427028:B1
2021-06-30
Patent
KR:1020210085926A
2023-09-07
2023-10-06
Weinberger M,Stirnemann E,Schmucki J,Windhab E,Mitra B
Bühler AG
Method for the production of protein-containing foods
The present invention relates to a method for producing protein-containing foamed food products, comprising the steps: metering raw materials into an extruder, wherein at least one raw material is a protein, mixing the raw materials into the extruder to produce a mixture, extruding the mixture to produce an extrudate, and leading the extrudate out of the extruder through a cooling die with cooling of the extrudate to a temperature of less than 100 °C, wherein pores are formed in a controlled man
The present invention provides a method for increasing collagen production in a cell and a method for inhibiting cell migration. Further, the present invention provides a pharmaceutical composition comprising lipopeptides, wherein the lipopeptides substantially consist of ETTES lipopeptides, and uses of said pharmaceutical composition. The invention also provides a supramolecular structure comprising lipopeptides, wherein the lipopeptides substantially consist of ETTES lipopeptides, as well as a
This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.