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Record
OAR or Target
Dose
Fractions
Conventional
Count73
1
2607
SpinalCord
45 Gy
2
1746
BrachialPlexs
62 Gy
3
183
BrachialPlexs
60 Gy
4
2597
Heart
25 Gy
5
393
Heart
20 Gy
6
394
Heart
10 Gy
7
2596
Heart
3 Gy
8
2598
Heart
25 Gy
9
395
Heart
20 Gy
10
396
Heart
10 Gy
11
2595
Heart
2 Gy
12
1337
Heart
40 Gy
13
385
Heart
35 Gy
14
387
Heart
20 Gy
15
1338
Heart
20 Gy
16
384
Heart
4 Gy
17
2592
Heart
2 Gy
18
409
Heart
25 Gy
19
408
Heart
25 Gy
20
407
Heart
4 Gy
21
442
Ventricle_L
25 Gy
22
2263
Ventricle_L
10 Gy
23
441
Ventricle_L
5 Gy
24
2262
Ventricle_L
5 Gy
25
1340
LAD
20 Gy
26
497
Lungs
20 Gy
27
2767
Lungs
20 Gy
28
1838
Lungs
18 Gy
29
3164
Lungs
6 Gy
30
3165
Lung_Ipsi
8 Gy
31
547
Lung_Ipsi
20 Gy
32
548
Lung_Ipsi
20 Gy
33
1339
Lung_Ipsi
20 Gy
34
549
Lung_Ipsi
10 Gy
35
550
Lung_Ipsi
10 Gy
36
2601
Lung_Ipsi
10 Gy
37
551
Lung_Ipsi
5 Gy
38
552
Lung_Ipsi
5 Gy
39
3163
Lung_Ipsi
5 Gy
40
560
Lung_Ipsi
20 Gy
41
561
Lung_Ipsi
10 Gy
42
562
Lung_Ipsi
5 Gy
43
2603
Lung_Contra
5 Gy
44
569
Lung_Contra
20 Gy
45
568
Lung_Contra
5 Gy
46
3011
ChestWall
130 Gy-EQD2(α/β=3)
47
611
Breast_Ipsi
105%
48
615
Breast_Contra
3.1 Gy
49
2605
Breast_Contra
3 Gy
50
616
Breast_Contra
1.86 Gy
51
1346
Breast_Contra
0 Gy
52
617
Breast_Contra
6 Gy
53
621
Breast_Contra
4.1 Gy
54
1341
CTVp_breast
110%
55
1342
CTVp_breast
107%
56
1343
CTVp_breast
105%
57
1344
CTVp_breast
95%
58
2577
PTVe_Breast/CW
120%
59
2578
PTVe_Breast/CW
107%
60
2576
PTVe_Breast/CW
95%
61
1206
PTVe_Breast/CW
62 Gy
62
1205
PTVe_Breast/CW
54 Gy
63
1204
PTVe_Breast/CW
47.5 Gy
64
1530
PTVe_Lump
95%
65
1527
PTV_LN_Axilla
115%
66
2584
PTV_LN_Axilla
95%
67
1207
PTV_LN_Axilla
47.5 Gy
68
1528
PTV_LN_SCV
115%
69
2583
PTV_LN_SCV
95%
70
1208
PTV_LN_SCV
47.5 Gy
71
1529
PTV_LN_IMN
115%
72
2585
PTV_LN_IMN
90%
73
1209
PTV_LN_IMN
45 Gy
74
3043
Thyroid_Glnd
3%
75
3044
Thyroid_Glnd
1.35 Gy
76
3042
Heart
5%
77
3040
Heart
5%
78
3038
Lung_Ipsi
30%
79
3039
Lung_Contra
5%
80
3036
Breast_Ipsi
50%
81
3037
Breast_Contra
100%
82
3034
PTV
110%
83
3032
PTV
90%
84
397
Heart
7 Gy
85
399
Heart
3 Gy
86
3005
Heart
1.35 Gy
87
398
Heart
1.5 Gy
88
557
Lung_Ipsi
10 Gy
89
3006
Lung_Ipsi
8.1 Gy
90
556
Lung_Ipsi
8 Gy
91
3009
Lung_Ipsi
2.7 Gy
92
571
Lung_Contra
5 Gy
93
612
Breast_Ipsi
105%
94
3007
Breast_Ipsi
25.65 Gy
95
613
Breast_Ipsi
15 Gy
96
3008
Breast_Ipsi
13.5 Gy
97
620
Breast_Contra
1 Gy
98
3010
Breast_Contra
0.81 Gy
99
1194
CTV
30 Gy
100
1165
PTV
110%
101
1164
PTV
107%
102
1163
PTV
105%
103
1167
PTV
105%
104
1162
PTV
95%
105
1503
PTV
95%
106
2477
PTV
31.5 Gy
107
1168
PTV
30 Gy
108
1169
PTV
28.5 Gy
109
1472
PTV
28 Gy
110
400
Heart
36 Gy
111
558
Lung_Ipsi
20 Gy
112
614
Breast_Ipsi
20 Gy
113
2608
SpinalCord
37.8 Gy
114
2512
Heart
35 Gy
115
411
Heart
22.5 Gy
116
2513
Heart
17 Gy
117
388
Heart
16 Gy
118
389
Heart
8 Gy
119
412
Heart
22.5 Gy
120
390
Heart
16 Gy
121
391
Heart
8 Gy
122
1335
Heart
35 Gy
123
1334
Heart
17 Gy
124
392
Heart
3.2 Gy
125
410
Heart
3 Gy
126
2599
Heart
1.6 Gy
127
2890
Heart
40 Gy
128
2891
Heart
18 Gy
129
2894
Heart
13 Gy
130
2892
Heart
10 Gy
131
2893
Heart
2 Gy
132
1336
LAD
17 Gy
133
2898
Lungs
25 Gy
134
2896
Lungs
20 Gy
135
2899
Lungs
17 Gy
136
2897
Lungs
12 Gy
137
2895
Lungs
10 Gy
138
2900
Lungs
8 Gy
139
2901
Lungs
6.36 Gy
140
563
Lung_Ipsi
18 Gy
141
2905
Lung_Ipsi
18 Gy
142
1333
Lung_Ipsi
17 Gy
143
553
Lung_Ipsi
16 Gy
144
2514
Lung_Ipsi
16 Gy
145
2602
Lung_Ipsi
10 Gy
146
554
Lung_Ipsi
8 Gy
147
2906
Lung_Ipsi
6 Gy
148
555
Lung_Ipsi
4 Gy
149
574
Lung_Contra
4.8 Gy
150
570
Lung_Contra
4 Gy
151
2902
Lung_Contra
2.5 Gy
152
2903
Lung_Contra
2.5 Gy
153
2904
Lung_Contra
1 Gy
154
1332
Breast_Ipsi
110%
155
1331
Breast_Ipsi
107%
156
1330
Breast_Ipsi
105%
157
1329
Breast_Ipsi
95%
158
2511
Breast_Ipsi
95%
159
2889
Breast_Contra
5 Gy
160
2888
Breast_Contra
3%
161
622
Breast_Contra
3 Gy
162
2606
Breast_Contra
3 Gy
163
618
Breast_Contra
2.4 Gy
164
619
Breast_Contra
1.44 Gy
165
1345
Breast_Contra
0 Gy
166
2579
PTVe_Breast/CW
115%
167
2581
PTVe_Breast/CW
107%
168
2582
PTVe_Breast/CW
95%
169
2590
PTV_LN_Axilla
110%
170
2591
PTV_LN_Axilla
95%
171
2587
PTV_LN_SCV
110%
172
2586
PTV_LN_SCV
95%
173
2588
PTV_LN_IMN
110%
174
2589
PTV_LN_IMN
90%
175
3247
95%
176
3218
PTVsb
110%
177
3220
PTVsb
107%
178
3219
PTVsb
105%
179
3233
PTVsb
95%
180
3252
PTVsb
27 Gy
Fractions
BID
Count10
Fractions
5
Count26
Fractions
10
Count3
Fractions
15-16
Count62
Fractions
General Metrics
Count6
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Dose Deviation
Volume
Volume Deviation
Metric Type
Importance
Site
Fractions
Intent
Landmark Pub
Protocol
Guidelines
Paper #1 Title
Paper #1 Link
Paper #2 Title
Paper #2 Link
RNI
Laterality
Mode
Notes
Contouring
Institution
50 Gy
0.035 cc
Dose limit
Must
Breast
NSCLC
SCLC
Conventional
General
CORSAIR
VA 🥇 Breast 2022
NCCN EsophGEJ 3.2023
NCCN Gastric 2.2023
DOSE-Pro Thoracic
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Cord (and medulla) 47.4 Gy (5 cc) and 52.8 Gy (0.035 cc); <b>Cord contouring instructions<b>: "Entire bony canal including at least 10 cm superior and inferior to PTV." Brainstem (not medulla) 52 Gy (5 cc) and 60 Gy (0.035 cc); <b>Brainstem (not medulla) contouring instructions<b>: "Superiorly from incisura, midbrain and pons only, 1 structure." 

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

3 cc
Volume limit
H&N
H&N: Nasopharynx
H&N: Oral Cavity
H&N: Oropharynx
Glioblastoma
Thyroid
Esophageal
Gastric
Breast
Mesothelioma
Sarcoma
NSCLC
SCLC
Conventional
General
Timmerman '21

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Brachial plexus 62 Gy (3 cc) and 66 Gy (0.035 cc). <b>Contouring instructions<b>: "Each side separately from the spinal nerves exiting the neuroforamina from around C5 to T2 to include only the major trunks of the brachial plexus using the subclavian and axillary vessels as a surrogate for identifying its location extending proximally at the bifurcation of the brachiocephalic trunk into the jugular/subclavian veins (o

Per the post-HyTEC brachial plexus paper <ll>Milano IJROBP '23!https://pubmed.ncbi.nlm.nih.gov/36682981/<ll>: "When delineating the brachial plexus, structures that assist with image segmentation are first identified, including the C4-5 and T1-2 neural foramina (best identified in the sagittal plane), the anterior and middle scalene muscles, and the subclavian neurovascular bundle. Next, the C5-T1 ventral rami are delineated, continuing caudally and laterally between the middle and anterior scal

UTSW
66 Gy
0.035 cc
0.1 cc
Dose limit
Should
H&N
H&N: Nasopharynx
H&N: Oral Cavity
H&N: Oropharynx
Thyroid
Esophageal
Gastric
Breast
Mesothelioma
Sarcoma
NSCLC
SCLC
H&N: Larynx
Conventional
General
Timmerman '21
CORSAIR
RTOG 0617
NRG HN005
VA 🥇 Breast 2022
Katsoulakis PRO '22
https://doi.org/10.1016/j.prro.2022.05.009

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Brachial plexus 62 Gy (3 cc) and 66 Gy (0.035 cc). <b>Contouring instructions<b>: "Each side separately from the spinal nerves exiting the neuroforamina from around C5 to T2 to include only the major trunks of the brachial plexus using the subclavian and axillary vessels as a surrogate for identifying its location extending proximally at the bifurcation of the brachiocephalic trunk into the jugular/subclavian veins (o

Per the post-HyTEC brachial plexus paper <ll>Milano IJROBP '23!https://pubmed.ncbi.nlm.nih.gov/36682981/<ll>: "When delineating the brachial plexus, structures that assist with image segmentation are first identified, including the C4-5 and T1-2 neural foramina (best identified in the sagittal plane), the anterior and middle scalene muscles, and the subclavian neurovascular bundle. Next, the C5-T1 ventral rami are delineated, continuing caudally and laterally between the middle and anterior scal

UTSW
Florida
30 Gy
10%
Volume limit
Breast
Conventional
General
QUANTEC
CORSAIR
NSABP B-51
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
Left

Regional nodal irradiation; left sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

25 Gy
5%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
Left

Left sided; 25 Gy if regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15 Gy
30%
35%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
Left

Left sided; 15 Gy if RNI

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5 Gy
mean
Dose limit
Breast
Conventional
General
MA.39
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Left

Left sided.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

30 Gy
2%
Volume limit
Breast
Conventional
General
NSABP B-51
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
Right

Regional nodal irradiation; right sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

25 Gy
0%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
Right

Right sided; 25 Gy if regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15 Gy
10%
15%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
Right

Right sided; 15 Gy if RNI

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5 Gy
mean
Dose limit
Breast
Conventional
General
MA.39
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Right

Right sided.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

3%
Volume limit
Breast
Conventional
General
DBCG HYPO
DBCG SKAGEN
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 60 Gy (15 cc), 40 Gy (20%), and 68 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

40 Gy
0.1 cc
Dose limit
Breast
Conventional
General
Needs source

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 60 Gy (15 cc), 40 Gy (20%), and 68 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
Conventional
General
DBCG SKAGEN

Per <ll>QUANTEC!https://pubmed.ncbi.nlm.nih.gov/20171522/<ll>: V25 < 10% is associated with a < 1% probability of cardiac mortality at ~15 years after RT.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No

Per <ll>QUANTEC!https://pubmed.ncbi.nlm.nih.gov/20171522/<ll>: V25 < 10% is associated with a < 1% probability of cardiac mortality at ~15 years after RT.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5 Gy
mean
Dose limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/

Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

3 Gy
mean
Dose limit
Breast
Conventional
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

30 Gy
5%
Volume limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Left
VMAT

Breast VMAT; Left sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
30 Gy
0%
Volume limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Right
VMAT

Breast VMAT; Right sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
5 Gy
mean
Dose limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
VMAT

Breast VMAT. Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
5%
Volume limit
Breast
Conventional
General
Needs source

LV and combined bilateral ventricles

38 cc
Volume limit
Breast
Conventional
General
NCCN Hodgkin 1.2024
Abraham IJROBP '22
https://pubmed.ncbi.nlm.nih.gov/35085715/
NCCN Hodgkin
https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1439

Per a prospective evaluation on a RCT concerning forward-planned vs. inverse planned IMRT for breast cancer <ll>Abraham IJROBP '22!https://pubmed.ncbi.nlm.nih.gov/35085715/<ll>, maintaining the LV volume receiving 5 Gy and 10 Gy to < 42 cc and < 38 cc, respectively, can reduce the risk of radiation related late cardiac events at 10 years to < 5% over baseline.

Test

10%
Volume limit
Breast
Conventional
General
Needs source

LV and combined bilateral ventricles

42 cc
Volume limit
Breast
Conventional
General
NCCN Hodgkin 1.2024
Abraham IJROBP '22
https://pubmed.ncbi.nlm.nih.gov/35085715/
NCCN Hodgkin
https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1439

Per a prospective evaluation on a RCT concerning forward-planned vs. inverse planned IMRT for breast cancer <ll>Abraham IJROBP '22!https://pubmed.ncbi.nlm.nih.gov/35085715/<ll>, maintaining the LV volume receiving 5 Gy and 10 Gy to < 42 cc and < 38 cc, respectively, can reduce the risk of radiation related late cardiac events at 10 years to < 5% over baseline.

Test

0.1 cc
Dose limit
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No

Pay attention to the 15 Gy IDL! Per <ll>Atkins JAMA Onc '20!https://pubmed.ncbi.nlm.nih.gov/33331883/<ll> (NSCLC): LV V15 ≥ 1% increased risk among patients with CHD, with 1y MACE for LV V15 ± 1% of 4→ 8%. Optimal cut points for substructure and RT doses were LAD V15 ≥ 10% (C-index 0.64), L Cx V15 ≥ 14% (0.64), LV V15 ≥ 1% (0.64) and mean total coronary artery dose ≥ 7 Gy (0.62) in regard to association with MACE and mortality in NSCLC. Additional data from the 2022 Atkins group <ll>McKenzie IJR

35%
40%
Volume limit
Thyroid
NSCLC
SCLC
Sarcoma
Kidney
Mesothelioma
Esophageal
Pediatrics
Breast
Conventional
General
QUANTEC
Timmerman '21
RTOG 0617
RTOG 1308
NCCN NSCLC 1.2024
DOSE-Pro Thoracic
NCCN NSCLC
https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1450

----

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

UTSW
33%
37%
Volume limit
Thyroid
NSCLC
SCLC
Sarcoma
Kidney
Mesothelioma
Esophageal
Pediatrics
Breast
Conventional
General
VA 🥇 Lung 2023
Puckett PRO '23
https://pubmed.ncbi.nlm.nih.gov/37075838/
NCCN NSCLC
https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1450

----

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

*950 cc
*1500 cc
CV
Thyroid
NSCLC
SCLC
Sarcoma
Kidney
Mesothelioma
Esophageal
Pediatrics
Breast
Conventional
General
Timmerman '21

Key: * = Complementary/critical/cold minimum volume. CVxGy[cc] ≥ y (i.e., volume receiving x[Gy] or less is greater than y[cc]) per <ll>TG-263!https://www.aapm.org/pubs/reports/RPT_263.pdf<ll> (Figure 4, p.24).

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

UTSW
mean
Dose limit
Breast
Conventional
General
De Rose RTO '24
https://pubmed.ncbi.nlm.nih.gov/39427931/
Puckett PRO '23
https://pubmed.ncbi.nlm.nih.gov/37075838/

----

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

mean
Dose limit
Breast
Conventional
General
De Rose RTO '24
https://pubmed.ncbi.nlm.nih.gov/39427931/

----

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15%
20%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
DBCG SKAGEN
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

35%
40%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
DBCG SKAGEN
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

25%
Volume limit
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

35%
40%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

50%
60%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
Yes
General

Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

65%
Volume limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

50%
55%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
No
General

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

65%
70%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
Yes
General

Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

75%
Volume limit
Breast
Conventional
General
Yes
General

Includes regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

30%
35%
Volume limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
VMAT

Breast VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
50%
60%
Volume limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
VMAT

Breast VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
65%
75%
Volume limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
VMAT

Breast VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
15%
Volume limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes

Regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5%
Volume limit
Breast
Conventional
General
Needs source
VMAT

Breast VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
15%
Volume limit
Breast
Conventional
General
RTOG 1005
VA 🥇 Breast 2022
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
VMAT

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

Ohio State
0.035 cc
Dose limit
No consensus
Breast
Conventional
Re-irradiation
Kaider-Person Clin Onc '18
https://doi.org/10.1016/j.clon.2017.11.004
Paradis ARO '19 (Michigan)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817723/

Per <ll>Kaider-Person Clin Onc '18!https://doi.org/10.1016/j.clon.2017.11.004<ll>: Low rates of toxicity were discovered when Dmax of < 130 Gy were generally employed. With Dmax from 88-126 Gy range, there was low rates of G3+ ulceration (3-8%) .and fibrosis (10-16%). Hence, Dmax from 126-130 Gy to chest wall may be reasonable. However, these values were retrieved from small series, using various radiotherapy schedules, volumes and techniques, and with scarce information about toxicity. Moreover

10%
Volume limit
Breast
Conventional
General
Patel IJROBP '19
https://pubmed.ncbi.nlm.nih.gov/30145393/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

4.96 Gy
0.1 cc
Dose limit
Breast
Conventional
General
Needs source
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

5 Gy
10%
Volume limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Regional nodal irradiation.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

3.1 Gy
5%
Volume limit
Breast
Conventional
General
RTOG 1005
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

ALARA
ALARA
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

mean
Dose limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
VMAT

Breast VMAT

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

5%
10%
Volume limit
Breast
Conventional
General
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
VMAT

Breast VMAT

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

Ohio State
0.1 cc
Dose limit
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

110%
2 cc
Dose limit
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

107%
2%
Dose limit
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Hotspots for 15 fractions defined as >105%, while >107% for conventional.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

95%
Dose coverage
Breast
Conventional
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

0.03 cc
Dose limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

10 cc
Dose limit
Breast
Conventional
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

90%
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

64 Gy
30%
35%
Dose limit
Breast
Conventional
General
NSABP B-51
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

Ohio State
56 Gy
50%
Dose limit
Breast
Conventional
General
NSABP B-51
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

Ohio State
45 Gy
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

Ohio State
90%
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

57.5 Gy
max
Dose limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51 Per Protocol: At least 95% of the Axillary PTV will receive 47.5 Gy which is 95% of the prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Axillary PTV will receive 45 Gy which is 90% of the prescribed dose of 50 Gy. Max point dose will be no more than 57.5 Gy which 115% of the prescription.

Ohio State
90%
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

45 Gy
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
General

NSABP B-51 Per Protocol: At least 95% of the Axillary PTV will receive 47.5 Gy which is 95% of the prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Axillary PTV will receive 45 Gy which is 90% of the prescribed dose of 50 Gy. Max point dose will be no more than 57.5 Gy which 115% of the prescription.

Ohio State
57.5 Gy
max
Dose limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51 Per Protocol: At least 95% of the SCL PTV will receive 47.5 Gy which is 95% of the prescribed dose of 50 Gy Variation Acceptable: At least 90% of the SCL PTV will receive 45 Gy which is 90% of the prescribed dose of 50 Gy. Max point dose will be no more than 57.5 Gy which 115% of the prescription.

Ohio State
90%
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

45 Gy
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
General

NSABP B-51 Per Protocol: At least 95% of the SCL PTV will receive 47.5 Gy which is 95% of the prescribed dose of 50 Gy Variation Acceptable: At least 90% of the SCL PTV will receive 45 Gy which is 90% of the prescribed dose of 50 Gy. Max point dose will be no more than 57.5 Gy which 115% of the prescription.

Ohio State
57.5 Gy
max
Dose limit
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51 Per Protocol: At least 95% of the IMN PTV will receive 45 Gy which is 90% of the prescribed dose of 50 Gy Variation Acceptable: At least 90% of the IMN PTV will receive 40 Gy which is 80% of the prescribed dose of 50 Gy. Max point dose will be no more than 57.5 Gy which 115% of the prescription.

Ohio State
90%
80%
Dose coverage
Breast
Conventional
General
NSABP B-51
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

NSABP B-51: REQUIRED Compliance Criteria: Per Protocol: At least 95% of the Chestwall or Breast PTV Eval will receive 47.5 Gy which is 95% of the chestwall or breast prescribed dose of 50 Gy Variation Acceptable: At least 90% of the Chestwall or Breast PTV Eval will receive 45 Gy which is 90% of the whole breast prescribed dose of 50 Gy.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

40 Gy
95%
90%
Dose coverage
Breast
Conventional
General
NSABP B-51
Bazan IJROBP '20
https://www.redjournal.org/article/S0360-3016(20)31446-2/abstract
General

NSABP B-51 Per Protocol: At least 95% of the IMN PTV will receive 45 Gy which is 90% of the prescribed dose of 50 Gy Variation Acceptable: At least 90% of the IMN PTV will receive 40 Gy which is 80% of the prescribed dose of 50 Gy. Max point dose will be no more than 57.5 Gy which 115% of the prescription.

Ohio State
5%
0.035 cc
Dose limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/

Per HN005 (OP): "The thyroid gland should be contoured in its entirety based on treatment planning CT scan. The thyroid gland has two connected lobes and is located inferior to the thyroid cartilage. The thyroid gland will have considerable contrast on contrast-enhanced CT compared to the surrounding tissues."

2.25 Gy
0.035 cc
Dose limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/

Per HN005 (OP): "The thyroid gland should be contoured in its entirety based on treatment planning CT scan. The thyroid gland has two connected lobes and is located inferior to the thyroid cartilage. The thyroid gland will have considerable contrast on contrast-enhanced CT compared to the surrounding tissues."

2.25 Gy
40%
45%
Volume limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
Left
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

2.25 Gy
5%
10%
Volume limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
Right
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

13.5 Gy
15%
20%
Volume limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

2.25 Gy
15%
20%
Volume limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

22.5 Gy
60%
65%
Volume limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

45 Gy
3%
5%
Volume limit
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

120%
0.035 cc
Dose limit
Must
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
General
40.5 Gy
90%
Dose coverage
Breast
BID
Re-irradiation
RTOG 1014
Arthur IJROBP '17
https://pubmed.ncbi.nlm.nih.gov/28721885/
General
5%
Volume limit
Breast
5
General
CORSAIR
UK FAST-Forward
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
No
General

Less than 1 cm of heart in field if possible.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
5
General
CORSAIR
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

4.05 Gy*
5%
8%
Volume limit
Breast
5
General
ACCEL
Grendarova IJROBP '23
https://pubmed.ncbi.nlm.nih.gov/37871884/
Grendarova JRO '18
https://link.springer.com/article/10.1007/s13566-018-0359-2
No
General

*Heart (region location specific) < 5% to receive ≥ 5% (right breast);10% (excluding lower inner quadrant);15% (left lower inner quadrant location) of the prescribed dose

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

30%
Volume limit
Breast
5
General
CORSAIR
UK FAST-Forward
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
No
General

Less than 1 cm of heart in field if possible.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

20%
Volume limit
Breast
5
General
CORSAIR
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
13%
Volume limit
Breast
5
General
ACCEL
Grendarova IJROBP '23
https://pubmed.ncbi.nlm.nih.gov/37871884/
Grendarova JRO '18
https://link.springer.com/article/10.1007/s13566-018-0359-2
No
General

Less than 2 cm strip of lung if possible.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15%
17%
Volume limit
Breast
5
General
CORSAIR
UK FAST-Forward
UK FAST
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
No
General

Less than 2 cm strip of lung if possible.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
13%
Volume limit
Breast
5
General
ACCEL
Grendarova IJROBP '23
https://pubmed.ncbi.nlm.nih.gov/37871884/
Grendarova JRO '18
https://link.springer.com/article/10.1007/s13566-018-0359-2
No
General

Less than 2 cm strip of lung if possible.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
5
General
CORSAIR
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

31.5 Gy
5%
Volume limit
Obsolete
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

25%
35%
Volume limit
Breast
5
General
ACCEL
Grendarova IJROBP '23
https://pubmed.ncbi.nlm.nih.gov/37871884/
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Ipsi breast - PTV

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

50%
60%
Volume limit
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Ipsi breast - PTV

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

50%
60%
Volume limit
Breast
5
General
ACCEL
Grendarova IJROBP '23
https://pubmed.ncbi.nlm.nih.gov/37871884/
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Ipsi breast - PTV

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

2 Gy
max
Dose limit
Breast
5
General
CORSAIR
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

3%
Dose limit
Breast
5
General
ACCEL
Grendarova IJROBP '23
https://pubmed.ncbi.nlm.nih.gov/37871884/
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

98%
Volume coverage
Breast
5
General
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General
0.1 cc
Dose limit
Breast
5
General
UK FAST-Forward
UK FAST
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
FAST Protocol
https://www.birpublications.org/doi/full/10.1259/bjr/32249628
No
General
2%
Volume limit
Breast
5
General
UK FAST-Forward
UK FAST
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
FAST Protocol
https://www.birpublications.org/doi/full/10.1259/bjr/32249628
No
General
5%
Volume limit
Breast
5
General
UK FAST-Forward
UK FAST
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
No
General
110%
max
Dose limit
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General


Per <ll>Florence!https://ascopubs.org/doi/full/10.1200/JCO.20.00650<ll>: Partial breast CTV defined as Clips + 1 cm (3 mm cropped from skin). Partial breast PTV defined as CTV + 1 cm, allowed 4 mm to lung and 3 mm from skin.

95%
Volume coverage
Must
Breast
Rectal
5
General
UK FAST-Forward
ACCEL
VA 🥇 Rectal 2022
FAST Forward Protocol
https://www.icr.ac.uk/our-research/centres-and-collaborations/centres-at-the-icr/clinical-trials-and-statistics-unit/clinical-trials/fast_forward_page
Myerson IJROBP '14
https://pubmed.ncbi.nlm.nih.gov/24606849/
No
General

Per <ll>VA Blue Ribbon Panel!https://dx.doi.org/10.1016/j.prro.2022.05.005<ll> (Rectal Cancer): "With regard to short course treatment, the Blue-Ribbon Panel felt it was important to establish benchmark DVH constraints for quality control as there is sparse literature in regard to SCRT. The panel consensus for organ at risk (OAR) constraints included bladder constraints V15 ≤ 50%, V25 ≤ 20%, and Dmean ≤ 2000 cGy, femoral head constraint of D5% ≤ 2000 cGy and small bowel constraints (defined as i

90%
0.1 cc
Dose limit
Breast
5
General
UK FAST
FAST Protocol
https://www.birpublications.org/doi/full/10.1259/bjr/32249628
No
General
100%
5%
10%
Volume limit
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General
95%
Volume coverage
Obsolete
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Per <ll>Florence!https://ascopubs.org/doi/full/10.1200/JCO.20.00650<ll>: Partial breast CTV defined as Clips + 1 cm (3 mm cropped from skin). Partial breast PTV defined as CTV + 1 cm, allowed 4 mm to lung and 3 mm from skin.

98%
95%
Volume coverage
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General

Per <ll>Florence!https://ascopubs.org/doi/full/10.1200/JCO.20.00650<ll>: Partial breast CTV defined as Clips + 1 cm (3 mm cropped from skin). Partial breast PTV defined as CTV + 1 cm, allowed 4 mm to lung and 3 mm from skin.

min
Dose coverage
Obsolete
Breast
5
General
Florence
Meattini JCO 2020
https://ascopubs.org/doi/full/10.1200/JCO.20.00650
Marrazzo PRO '22
https://www.sciencedirect.com/science/article/pii/S1879850022001862?via%3Dihub
No
General
0.035 cc
0.1 cc
Dose limit
Breast
10
General
MSKCC Braunstein IJROBP '19
https://www.sciencedirect.com/science/article/pii/S0360301619303062?via%3Dihub
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 36.6 Gy (15 cc) and 42.5 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

MSKCC
3%
Volume limit
Breast
10
General
MSKCC Braunstein IJROBP '19
https://www.sciencedirect.com/science/article/pii/S0360301619303062?via%3Dihub
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 16 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 15 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

MSKCC
45%
50%
Volume limit
Breast
10
General
MSKCC Braunstein IJROBP '19
https://www.sciencedirect.com/science/article/pii/S0360301619303062?via%3Dihub
No
General

Ipsi breast - PTV

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

MSKCC
42 Gy
0.035 cc
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Cord (and medulla) 39 Gy (5 cc) and 42 Gy (0.035 cc); <b>Cord contouring instructions<b>: "Entire bony canal including at least 10 cm superior and inferior to PTV." Brainstem (not medulla) 40 Gy (5 cc) and 44 Gy (0.035 cc); <b>Brainstem (not medulla) contouring instructions<b>: "Superiorly from incisura, midbrain and pons only, 1 structure."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5%
Volume limit
Breast
15-16
General
DBCG PBI
Offersen JCO '22
https://pubmed.ncbi.nlm.nih.gov/35930754/
Left

Left sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

27 Gy
10%
Volume limit
Breast
15-16
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
Left

Left sided, regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
15-16
General
DBCG PBI
Offersen JCO '22
https://pubmed.ncbi.nlm.nih.gov/35930754/
Left

Left sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

20 Gy
5%
Volume limit
Breast
15-16
General
RTOG 1005
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
Left

Left sided, no regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

30%
35%
Volume limit
Breast
15-16
General
RTOG 1005
Left

Left sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

27 Gy
2%
Volume limit
Breast
15-16
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
Right

Right sided, regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

20 Gy
0%
Volume limit
Breast
15-16
General
RTOG 1005
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
Right

Right sided, no regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
15%
Volume limit
Breast
15-16
General
RTOG 1005
Right

Right sided

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5%
Volume limit
Breast
15-16
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 42 Gy (15 cc) and 48.9 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
15-16
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

4 Gy
mean
Dose limit
Breast
15-16
General
RTOG 1005

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5 Gy
mean
Dose limit
Breast
15-16
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Rice Rad Onc '16
https://pubmed.ncbi.nlm.nih.gov/27639373
Yes

Regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

2.4 Gy
mean
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

3%
Volume limit
Breast
15-16
General
CORSAIR
De Rose Rad Onc '16
https://pubmed.ncbi.nlm.nih.gov/27639373
VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 42 Gy (15 cc) and 48.9 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5%
Volume limit
Breast
15-16
General
CORSAIR
De Rose Rad Onc '16
https://pubmed.ncbi.nlm.nih.gov/27639373
VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 42 Gy (15 cc) and 48.9 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

2%
10%
Volume limit
Breast
15-16
General
CORSAIR
UK FAST-Forward
Rice Rad Onc '16
https://pubmed.ncbi.nlm.nih.gov/27639373
VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 42 Gy (15 cc) and 48.9 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

5%
Volume limit
Breast
15-16
General
CORSAIR
UK FAST-Forward
Murray Lancet '20
https://pubmed.ncbi.nlm.nih.gov/32580883
VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 42 Gy (15 cc) and 48.9 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

30%
Volume limit
Breast
15-16
General
CORSAIR
UK FAST-Forward
Murray Lancet '20
https://pubmed.ncbi.nlm.nih.gov/32580883
VMAT

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Heart/pericardium 42 Gy (15 cc) and 48.9 Gy (0.035 cc). <b>Contouring instructions<b>: "Contoured along with the pericardial sac; the superior aspect (or base) for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

20 Gy
0.1 cc
Dose limit
Breast
15-16
General
CORSAIR
DBCG HYPO
DBCG PBI
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
Offersen JCO '22
https://pubmed.ncbi.nlm.nih.gov/35930754/
No

DBCG reportedly doesn't use this contraint anymore. Just contour heart, ensuring LAD in contour, and try to limit heart Dmax to 17-20 Gy.

5%
Volume limit
Breast
15-16
General
CORSAIR
Tolia World J Radiol '11
https://pubmed.ncbi.nlm.nih.gov/22013502

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Dose limit
Breast
15-16
General
CORSAIR
De Rose Rad Onc '16
https://pubmed.ncbi.nlm.nih.gov/27639373

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

8%
Volume limit
Breast
15-16
General
CORSAIR
Tolia World J Radiol '11
https://pubmed.ncbi.nlm.nih.gov/22013502

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15%
Volume limit
Breast
15-16
General
CORSAIR
UK FAST-Forward
Murray Lancet '20
https://pubmed.ncbi.nlm.nih.gov/32580883

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

mean
Dose limit
Breast
15-16
General
CORSAIR
De Rose Rad Onc '16
https://pubmed.ncbi.nlm.nih.gov/27639373

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
15-16
General
CORSAIR
Tolia World J Radiol '11
https://pubmed.ncbi.nlm.nih.gov/22013502

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

mean
Dose limit
Breast
15-16
General
CORSAIR
Tolia World J Radiol '11
https://pubmed.ncbi.nlm.nih.gov/22013502

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

35%
40%
Volume limit
Breast
15-16
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
Volume limit
Breast
15-16
General
CORSAIR
Rice Breast Ca Targets Ther '17
https://pubmed.ncbi.nlm.nih.gov/28652810
Yes
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

25%
Volume limit
Breast
15-16
General
DBCG HYPO
DBCG PBI
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15%
20%
Volume limit
Breast
15-16
General
RTOG 1005
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

mean
Dose limit
Breast
15-16
General
DBCG PBI
Offersen JCO '22
https://pubmed.ncbi.nlm.nih.gov/35930754/
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

68%
Volume limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

35%
40%
Volume limit
Breast
15-16
General
RTOG 1005
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

mean
Dose limit
Breast
15-16
General
CORSAIR
Rice Breast Ca Targets Ther '17
https://pubmed.ncbi.nlm.nih.gov/28652810
Yes
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

50%
55%
Volume limit
Breast
15-16
General
RTOG 1005
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>: Lung 18 Gy (37%). Lung (minus GTV) minimum volume spared (MVS) from 16.5 Gy (males: 1500 cc*; females: 950 cc*). *One-third of "native" total organ volume (before any resection or volume reducing disease), whichever is greater.  <b>Contouring instructions<b>: "Contour right and left lung as 1, structure including all parenchymal lung tissue but excluding the GTV and major airways (trachea and main/lobar bronchi)."

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
15%
Volume limit
Breast
15-16
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

10%
15%
Volume limit
Breast
15-16
General
RTOG 1005
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

15%
Volume limit
Breast
15-16
General
CORSAIR
Tolia World J Radiol '11
https://pubmed.ncbi.nlm.nih.gov/22013502
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

3%
Volume limit
Breast
15-16
General
CORSAIR
Rice Breast Ca Targets Ther '17
https://pubmed.ncbi.nlm.nih.gov/28652810
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

mean
Dose limit
Breast
15-16
General
CORSAIR
Rice Breast Ca Targets Ther '17
https://pubmed.ncbi.nlm.nih.gov/28652810
General

Per <ll>Timmerman IJROBP '21!https://doi.org/10.1016/j.ijrobp.2021.09.027<ll>:

0.1 cc
Dose limit
Breast
15-16
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

110%
2 cc
Dose limit
Breast
15-16
General
DBCG HYPO
DBCG PBI
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
Offersen JCO '22
https://pubmed.ncbi.nlm.nih.gov/35930754/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

107%
2%
Dose limit
Breast
15-16
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Hotspots for 15 fractions defined as >105%, while >107% for conventional.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

95%
Dose coverage
Breast
15-16
General
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

100%
Dose coverage
Breast
15-16
General
DBCG PBI
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
Offersen JCO '22
https://pubmed.ncbi.nlm.nih.gov/35930754/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

15%
Volume limit
Breast
15-16
General
CORSAIR
Rudra JACMP '14
https://doi.org/10.1120%2Fjacmp.v15i2.4547
Noël Cancer '22
https://doi.org/10.1016%2Fj.canrad.2021.11.001
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

max
Dose limit
Breast
15-16
General
CORSAIR
Tolia World J Radiol '11
https://pubmed.ncbi.nlm.nih.gov/22013502
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

10 Gy
10%
Volume limit
Breast
15-16
General
RT CHARM
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

5 Gy
10%
Volume limit
Breast
15-16
General
RT CHARM
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
Yes
General

Regional nodal irradiation.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

3.84 Gy
0.1 cc
Dose limit
Breast
15-16
General
RTOG 1005
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

2.40 Gy
5%
Volume limit
Breast
15-16
General
RTOG 1005
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
No
General

No regional nodal irradiation.

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

ALARA
ALARA
Breast
15-16
General
CORSAIR
DBCG HYPO
Thomsen CTRO '21
https://pubmed.ncbi.nlm.nih.gov/33937532/
No
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

0.03 cc
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

10 cc
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

90%
95%
90%
Dose coverage
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

max
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General
90%
95%
90%
Dose coverage
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

max
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General
90%
95%
90%
Dose coverage
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

max
Dose limit
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General
90%
80%
Dose coverage
Breast
15-16
General
VA 🥇 Breast 2022
Puckett PRO '22
https://pubmed.ncbi.nlm.nih.gov/36115498/
General

Atlases: <ll>NRG!https://www.nrgoncology.org/ciro-breast<ll>, <ll>ESTRO!https://www.ncbi.nlm.nih.gov/pubmed/26791404<ll>, <ll>RADCOMP!https://www.rtog.org/CoreLab/ContouringAtlases/RADCOMPBreastAtlas.aspx<ll>

95%
90%
Dose coverage
Must
General
Breast
General Metrics
General
115%
0.03cc
Dose limit
Must
General
Breast
General Metrics
General
5%
10 cc
Volume limit
Should
General
Breast
General Metrics
General
10%
Volume limit
Should
General
Breast
General Metrics
General
90%
95%
90%
Dose coverage
Must
General
Breast
General Metrics
General
25 Gy
min
Dose coverage
Must
General
Breast
General Metrics
General
180 records

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