Cardiovascular disease is the largest cause of death worldwide with a contribution of around 30% of global mortality. Screening for these diseases may be done by assessing the increase in arterial stiffness. This can be done by calculating carotid-femoral pulse-wave velocity (cf-PWV), a biomarker that can reliably be measured via, amongst others, laser-doppler vibrometry (LDV). A prototype utilizing this technology was developed within the scope of the CARDIS (& subsequently the INSIDE) project.

Partial nephrectomy is the optimal surgery for early-stage renal tumours. Selective clamping (only clamping those arteries that perfuse maximal tumour and minimal healthy tissue) lowers the risk of excessive bleeding during tumour resection, while safeguarding the remaining healthy tissue’s renal function. To clamp successfully, insight in the patient-specific perfusion zones is necessary, which cannot be provided by CT-scans. Therefore, we propose a 3D renal perfusion model, which we validated