ISEMPH 2023 Tuesday
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Title
Day/Time
Session name
Location
Format
Duration
Full Name
Authors
Abstract
Email
Chair/Introducer
Background
Keywords
Permission to videotape
Session number
TUESDAY BREAKFAST
8/15/2023
7:30am
Tuesday Breakfast
Atrium
Other
1:00
Opening remarks
8/15/2023
8:45am
Opening remarks
Auditorium
Talk
0:15
Rühli, Labov, Nuñez De La Mora, Fox
Frank Rühli
Opening remarks
Embedded racism: A critical yet neglected health determinant in Evolutionary Medicine
8/15/2023
9:00am
Keynote
Auditorium
Plenary talk
1:00
Joseph L. Graves, Jr.
Joseph L. Graves, Jr.
Racial health disparities are a pervasive feature of modern experience and structural racism is increasingly recognized as a public health crisis. Yet evolutionary medicine has not adequately addressed the racialization of health and disease, particularly the systematic embedding of social biases in biological processes leading to disparate health outcomes delineated by socially defined race. In contrast to the sheer dominance of medical publications which still assume genetic ‘race’ and omit me
Michael Muehlenbein
Faculty
Keynote 1
TUESDAY MORNING COFFEE BREAK
8/15/2023
10:00am
Coffee break 2
Atrium
Other
0:30
Coffee
Developing phage therapy through the lens of evolutionary medicine
8/15/2023
10:30am
Antibiotic resistance
Huntington room
Talk
0:15
Paul Turner
Paul Turner, Yale University School of Medicine, New Haven
Bacteriophage therapy, which uses lytic viruses as antimicrobials, has received renewed interest to address the emerging antimicrobial resistance (AMR) crisis. Cystic fibrosis (CF), a disease complicated by recurrent Pseudomonas aeruginosa pulmonary infections that cause lung function decline, exemplifies how AMR is already a clinical problem. We developed a treatment strategy to use bacteriophages that target bacterial cell surface receptors which contribute to antibiotic resistance or virulenc
paul.turner@yale.edu
Paul Turner
Faculty
Please post a videotape of my talk online if posting is possible
2
The sex-dependent impact of violence during pregnancy on offspring neurodevelopment: a birth cohort study.
8/15/2023
10:30am
Stress
Auditorium
Talk
0:15
Lukas Blumrich
Lukas Blumrich, Department of Pediatrics, Faculty of Medicine, University of São Paulo, São Paulo, Brazil; Marco Antônio Barbieri Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto; Vanda Maria Ferreira Simões, Department of Public Health, University of Maranhão, São Luís; Antonio Augusto Moura da Silva, Department of Public Health, University of Maranhão, São Luís; Heloisa Bettiol, Department of Pediatrics, Ribeirão Preto Medical School, University
Background: Stress during pregnancy can have lasting impacts on the developing fetus. The resultant developmental pathways may not only originate from disruption but also configure adaptation strategies. As a result, sexual dimorphism plays an important role. Violence during pregnancy (VDP) is a well-established stressor, but its effects on offspring are not clear. We hypothesized that VDP may have a sex-specific impact on offspring’s neuropschomotor development. Methods: With data from two Braz
lukas.blumrich@fm.usp.br
Mark Flinn
Graduate/medical student
stress; pregnancy; reproduction; violence; intimate partner violence;
Please post a videotape of my talk online if posting is possible
1
Novel Multidrug Resistance Region in an Environmental Escherichia coli Evolved from Multiple Transposable Elements
8/15/2023
10:45am
Antibiotic Resistance
Huntington room
Talk
0:15
Isabel Suarez
Isabel Suarez, University of California, Irvine; Andrei Tatarenkov, University of California, Irvine; Marlene de la Cruz University of California, Irvine; Luis Mota-Bravo, University of California, Irvine.
Antibiotic resistance in bacteria is a rising global health crisis, killing at least one million people per year worldwide. The extensive use of antibiotics in the clinic, veterinary medicine and agriculture has resulted in the evolution of multidrug resistant bacteria. Here, we hypothesize that environmental Escherichia coli are a large reservoirs of antibiotic resistance genes (ARGs) that have been mobilized by transposon and insertion sequences (ISs) in conjugative plasmids of different incom
suarezia@uci.edu
Paul Turner
Undergraduate
Antibiotic resistance, Escherichia coli, environment, evolution, horizonal gene transfer
Please post a videotape of my talk online if posting is possible
2
Association between prenatal exposure to domestic violence and earlier age at menarche in offspring.
8/15/2023
10:45am
Stress
Auditorium
Talk
0:15
Anna Carolina Berkenbrock Mendes
Anna Carolina Berkenbrock Mendes, University of São Paulo, Brazil; Karolina Silva Ferreira, University of São Paulo, Brazil; Maria Teresa Bechere Fernandes, University of São Paulo, Brazil; Thais Moura Ribeiro do Valle Nascimento, University of São Paulo, Brazil; Alexandre Archanjo Ferraro, University of São Paulo, Brazil.
Intimate partner violence (IPV) is an extremely prevalent problem worldwide, and can stand as an even greater issue when committed during pregnancy. Despite having ample data about the short-term consequences of IPV to both mother and child, literature still lacks evidence of long-term effects to the offspring. Unfavorable prenatal environments can influence the development of different non-communicable diseases. Therefore, this research aimed at finding if IPV during pregnancy (stressful prenat
anna.cbmendes@fm.usp.br
Mark Flinn
Graduate/medical student
prenatal exposure; stress; menarche; violence
Please post a videotape of my talk online if posting is possible
1
Utter unpredictability of the fitness effects of resistance mutations across environments in Escherichia coli
8/15/2023
11:00am
Antibiotic resistance
Huntington room
Talk
0:15
Alex Wong
Alex Wong, Texas A&M, USA André Amado, Universität Bern, Switzerland Rees Kassen, University of Ottawa, Canada Claudia Bank, Universität Bern, Switzerland Aaron Hinz, University of Ottawa, Canada
The evolution of antimicrobial resistance (AMR) in bacteria is a major public health concern. When resistance is highly prevalent in a pathogen population, antibiotic restriction protocols are often implemented to reduce their spread. These measures rely on fitness costs imposed by AMR, which in principle result in resistant strains being outcompeted by susceptible strains during the period of restriction. However, the magnitude of fitness deficits caused by resistance mutations can vary dependi
alex.wong@ag.tamu.edu
Paul Turner
Faculty
Antimicrobial resistance, genotype x environment interactions, predictability
Please post a videotape of my talk online if posting is possible
2
Association of pica with cortisol and inflammation among Latina pregnant women
8/15/2023
11:00am
Stress
Auditorium
Talk
0:15
Dayoon Kwon
Dayoon Kwon, UCLA Department of Epidemiology; Delaney A. Knorr, UCLA Department of Anthropology; Kyle S. Wiley, UCLA Department of Anthropology and UCLA Department of Psychiatry and Biobehavioral Sciences; Lyra Johnson, Northwestern University Department of Anthropology; Sera L. Young, Northwestern University Department of Anthropology; Molly M. Fox, UCLA Department of Anthropology and UCLA Department of Psychiatry and Biobehavioral Sciences.
Pica, the urge to consume items generally not considered food, such as dirt, raw starch, and ice, are particularly common among pregnant women. However, the biological causes and consequences of pica in pregnancy are not well understood. Therefore, this study aimed to assess how pica relates to endocrine stress and immune biomarkers in a cohort of pregnant Latina women in Southern California. Thirty-four women completed a structured pica questionnaire. Maternal urinary cortisol and plasma cytoki
dayoonk@ucla.edu
Mark Flinn
Graduate/medical student
Pica, stress, immune, pregnancy, cravings
Please delete any videotape made of my presentation
1
Evolutionary logic for use of cortisol as a biomarker
8/15/2023
11:15am
Stress
Auditorium
Talk
0:15
Mark Flinn
Mark Flinn, Baylor University, Waco; Blair Coe Schweiger, Baylor University, Waco; Anna Samsonov, Baylor University, Waco; Zahabia Kanchwala, Baylor University, Waco; Meena Meiyyappan, Baylor University, Waco; Samuel Urlacher, Baylor University, Waco
Use of cortisol as a biomarker in the medical, social, and behavioral sciences increased exponentially since development of ligand assay techniques in the 1980s (PubMed 1980 n=3; 2022 n=536). Here we present results from a scoping review of >5,000 research and clinical studies that use cortisol assayed from minimally invasive samples. Most of these studies are underpinned on the premise that cortisol is an objective measure of “stress.” We identify three key issues: (1) understanding of the
mark_flinn@baylor.edu
Mark Flinn
Faculty
Cortisol, evolutionary design, methodology, biomarker
Please post a videotape of my talk online if posting is possible
1
Evolutionary Medicine Goes to Space: How an Understanding of Tensegrity in Health and Disease Provides Insights into the Effects of Gravitational Changes
8/15/2023
11:30am
Evolutionary Medicine Goes to Space: How an Understanding of Tensegrity in Health and Disease Provides Insights into the Effects of Gravitational Changes
Huntington room
Workshop
1:00
Elizabeth Uhl
Nicole Bender, MD, PhD nicole.bender@iem.uzh.ch Alexandra Fahrner, PhD alexandra.fahrner@uzh.ch www.iem.uzh.ch
Through case-based discussions this workshop uses an evolutionary perspective to investigate the interplay between gravity and the tension-based (tensegrity) architecture of life to understand the health effects of space travel. Specifically, we discuss the impacts of space travel on musculoskeletal, cardiovascular and neurological systems. Comparing these impacts with the tensegrity disruptions that characterize specific diseases allows insights into the effects of exposure to different gravita
euhl@uga.edu
Nicole Bender & Alexandra Fahrner
Tensegrity, Mechanotransduction, Gravitational physiology, Space medicine
Workshop 1
How women’s immunoregulatory phenotypes during pregnancy relate to their own childhood history of microbial exposure
8/15/2023
11:30am
Women's reproductive biology
Auditorium
Talk
0:15
Molly Fox
Molly M. Fox, University of California, Los Angeles, Los Angeles, CA Adiba Hassan, UCLA Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA Kyle S. Wiley, University of California, Los Angeles, Los Angeles, CA Dayoon Kwon, UCLA Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA Delaney A. Knorr, University of California, Los Angeles, Los Angeles, CA
Previous studies found that children with siblings, farm residence, and other signs of greater microbial contacts had lower rates of hyper-responsive inflammatory pathologies. Pregnancy relies on intrinsic immunosuppressive function, yet it remains elusive how immunoregulation in pregnant women relates to their early-life microbial exposures. We examine whether childhood microbial exposures prime women’s pregnancy-related immunoregulatory capacity. Among N=55 pregnant women, we administered retr
mollyfox@ucla.edu
Molly Fox
Faculty
hygiene hypothesis, old friends hypothesis, pregnancy, immune function, women's reproductive health
Please post a videotape of my talk online if posting is possible
3
Hormonal Contraceptive Use and Women’s Inflammatory Response to Psychosocial Stress
8/15/2023
11:45am
Women's reproductive biology
Auditorium
Talk
0:15
Summer Mengelkoch
Summer Mengelkoch, University of California, Los Angeles, Los Angeles; Sarah E. Hill, Texas Christian University, Fort Worth; George Slavich, University of California, Los Angeles, Los Angeles
Women have been historically excluded from stress research; however, some past work finds women using hormonal contraceptives (HCs) exhibit a blunted cortisol response to stress, which may accompany an exaggerated inflammatory response to stress, although this has yet to be investigated in vivo. In the current research, participants included naturally cycling (NC) women (n = 67) and women using oral HCs (n = 60), who were all exposed to the stress condition of the Trier Social Stress Task. Befor
smengelkoch@mednet.ucla.edu
Molly Fox
Fellow/postdoc
Stress, Inflammation, Women's Health, Hormonal Contraceptives, Depression
Please post a videotape of my talk online if posting is possible
3
Prenatal Psychological Distress and a Novel Biomarker of Placental Invasiveness
8/15/2023
12:00pm
Women's reproductive biology
Auditorium
Talk
0:15
Delaney Knorr
Delaney Knorr, UCLA, Los Angeles, CA; Yazhen Zhu, UCLA, Los Angeles, CA; Hsian-Rong Tseng, UCLA, Los Angeles, CA; Molly Fox, UCLA, Los Angeles, CA.
We can apply evolutionary theory, such as maternal-fetal conflict in pregnancy, to better understand the risk factors and mechanisms of obstetric complications and adverse birth outcomes. Here, we test the prediction that maternal distress will exacerbate the divergence of maternal and fetal adaptive strategies through the attenuation of placental invasion. We employ a novel method to track placental changes across pregnancy in a cohort of 42 pregnant Latina women. We measure maternal anxiety an
d.knorr@ucla.edu
Molly Fox
Graduate/medical student
Maternal-fetal conflict; placental invasion; maternal prenatal psychological distress; pregnancy
Please post a videotape of my talk online if posting is possible
3
Sperm cells attacking implantation-stage blastocysts: quality check, birth control or microchimerism?
8/15/2023
12:15pm
Women's reproductive biology
Auditorium
Talk
0:15
Jayasree Sengupta
Jayasree Sengupta*, All India Institute of Medical Sciences, New Delhi, India; Thomas Kroneis*, Medical University of Graz, Graz, Austria; Amy M. Boddy, University of California, Santa Barbara, USA; Rahul Roy, Indian Statistical Institute, New Delhi, India; Anish Sarkar, Indian Statistical Institute, New Delhi, India; Deepayan Sarkar, Indian Statistical Institute, New Delhi, India; Debabrata Ghosh**, All India Institute of Medical Sciences, New Delhi, India; Berthold Huppertz**, Medical Universi
The mammalian embryo at blastocyst stage derives from fusion of an oocyte with a single sperm, followed by differentiation to result in an implantation-ready blastocyst consisting of cells of the inner cell mass and the trophectoderm. To initiate implantation, the blastocyst hatches from its protective zona pellucida and presents itself without a covering of extracellular matrix to the maternal uterine environment. This results in a period of a few hours between hatching and nidation where the b
thomas.kroneis@medunigraz.at
Molly Fox
Faculty
azonal blastocyst, mid-luteal phase, sperm competition, trophectoderm, ultrastructure, microchimerism
Please post a videotape of my talk online if posting is possible
3
TUESDAY LUNCH
8/15/2023
12:30pm
Lunch 1
Atrium
Other
1:00
Lunch
The joint contributions of air pollution and neighborhood deprivation on mental health trajectories in adolescence
8/15/2023
1:30pm
Air & Climate
Auditorium
Talk
0:15
Kyle Wiley
Kyle Wiley, University of California Los Angeles, CA, USA; Carlye Chaney, Yale University, CT, USA
Urban environments are unique relative to those in which hominins evolved and pose challenges to human health and well-being. Air pollution and neighborhood deprivation are features of urban environments that often occur in parallel and are associated with adverse adolescent mental health outcomes. However, these associations have largely been explored using cross-sectional analyses. We investigated whether air pollution and neighborhood deprivation were jointly associated with longitudinal traj
kyleswiley@ucla.edu
Charlie Nunn
Fellow/postdoc
air pollution; neighborhood deprivation; mental health; urban health
Please post a videotape of my talk online if posting is possible
4
Niveau Diagnosis in Evolutionary Medicine
8/15/2023
1:30pm
Niveau Diagnosis in Evolutionary Medicine
Huntington room
Workshop
1:00
Noel Boaz
Noel Boaz, ntboaz@earthlink.net Nicole Bender, nicole.bender@iem.uzh.ch, https://www.iem.uzh.ch/en/people/clinicalevol/Nicole-Bender.html Elizabeth Uhl, euhl@uga.edu, https://vet.uga.edu/person/elizabeth_uhl/ Robert L. Chevalier, RLC2M@virginia.edu https://med.virginia.edu/chrc/key-investigators/robert-l-chevalier-m-d/
The goals of the workshop are 1) to engage evolutionary biologists more fully in contributing to improve medical diagnoses, and 2) to involve clinicians in their role as diagnosticians to work with basic scientists and educators in evolutionary medicine “to incorporate evolutionary insights to improve medical research and practice.” “Niveau diagnosis” is an old term meaning “localization of an exact level of a lesion” that will be revised to operationalize diagnoses addressing “Tinbergen’s four
noeltboaz@integrativemedsci.org
Noel Boaz, Nicole Bender & Elizabeth Uhl
Evolutionary Medicine, Niveau Diagnosis, Evo-Devo, Ultimate Etiology, Pathology
Workshop 2
Evolution-Guided Biomedical Innovation: Leveraging Evolved Adaptations to Ambient Volcanic Particulate Matter in Other Species for Human Health
8/15/2023
1:45pm
Air & Climate
Auditorium
Talk
0:15
Emmily Schwitzer
Emily Schwitzer, MD. Division of Pulmonary and Critical Care at UCLA Barbara Natterson-Horowitz, MD. Division of Cardiology at UCLA. Department of Human Evolutionary Biology at Harvard.
ABSTRACT: Among the most devastating consequences of accelerated anthropogenic environmental change are the adverse effects of particulate air pollution now linked to nearly 7 million human deaths/year.1 A growing body of evidence supports a direct connection between rising levels of air pollution and a range of cardiopulmonary, developmental, reproductive, neurological and other pathologies.1-3 Countering these effects is a research priority: the evolved adaptations of other species may provid
eschwitzer@mednet.ucla.edu
Charlie Nunn
Clinician/health professional
Air pollution; comparitive; lung disease; volcanic ash; environmental exposure
Please post a videotape of my talk online if posting is possible
4
Climate Change and Health: Where is Evolutionary Medicine?
8/15/2023
2:00pm
Air & Climate
Auditorium
Talk
0:15
Charles Nunn
Charles Nunn, Duke University, Durham NC USA; Georgia Titcomb, Colorado State University, Fort Collins CO USA; John Uelmen, Duke University, Durham NC USA
Human-driven climate change poses an existential threat to human populations, with effects that include rising oceans, increased extreme weather events, loss of ecosystem services, and disruptions to agricultural and economic systems. Climate change also has well-established effects on multiple dimensions of human health. Although largely missing from investigations of climate change and health (CCH), evolutionary medicine is essential for understanding many dimensions of CCH, including evolut
clnunn@duke.edu
Charlie Nunn
Faculty
climate change, infectious disease, anthropogenic effects, evolutionary mismatch, global health
Please post a videotape of my talk online if posting is possible
4
Childhood activity patterns in the BaYaka hunter-gatherers.
8/15/2023
2:30pm
Non-western population health
Auditorium
Talk
0:15
Luke Kretschmer
Luke Kretschmer, University College London; Mark Dyble, University College London; David Bann, University College London; Gül Deniz Salali, University College London
Physical activity in childhood is important for healthy development, yet most children fail to meet health guidelines. Given the high levels of activity observed in adult hunter-gatherers, an understanding of how active children are, as they transition from playful children into adult foragers may help highlight shortcomings in post-industrial populations. Working with 35 BaYaka children (Boys: 19; Ages: 5-17 years) from Congo-Brazzaville, we quantified physical activity using wrist worn triaxia
ucsaldw@ucl.ac.uk
Alejandra Núñez- de la Mora
Graduate/medical student
Physical Activity, Hunter-Gatherer, Childhood, Energetics
Please delete any videotape made of my presentation
5
Teaching clinicians to employ insights from evolution to maintain compassion and reduce burnout: A demonstration workshop and discussion
8/15/2023
2:30pm
Teaching clinicians to employ insights from evolution to maintain compassion and reduce burnout: A demonstration workshop and discussion
Huntington room
Workshop
1:00
Andrew Shaner
Andrew Shaner, University of California, Los Angeles andrew.shaner@va.gov Sae Takada, University of California, Los Angeles STakada@mednet.ucla.edu Rachel Dajani, University of California, Los Angeles Rachel.Dajani@va.gov https://www.uclahealth.org/departments/medicine/internal-medicine/im-residency/equity-diversity-inclusion/faculty-spotlights Yue Ming Huang, University of California, Los Angeles yhuang@mednet.ucla.edu) https://www.sim.ucla.edu/our_team Daniel M T Fessler, University of Ca
At a clinic specializing in treating Veterans experiencing homelessness, we leverage evolutionary perspectives on social-relational cognition and affect to teach clinicians how to remain compassionate with patients who are angry, threatening, poorly adherent, or suffering severe mental or substance use disorders. We explain that treating everyone equally well is evolutionarily novel and runs counter to mental mechanisms evolved to protect against exploitation, assault, and infection. We show ho
andrew.shaner@va.gov
Andrew Shaner
Compassion Fatigue, Medical Education, Evolutionary Mismatch, Emotions, Cooperation, Evolutionary Psychology
Workshop 3
Testosterone is positively associated with coronary artery calcium in a low cardiovascular disease risk population
8/15/2023
2:45pm
Non-western population health
Auditorium
Talk
0:15
Benjamin Trumble
Benjamin C. Trumble PhD, Arizona State University, Tempe AZ, USA; Jacob Negrey PhD, Arizona State University, Tempe AZ, USA; Stephanie V. Koebele PhD, Arizona State University, Tempe AZ, USA; Randall C. Thompson MD, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA; L. Samuel Wann MD, Ascension Healthcare, Milwaukee, WI, USA; Adel H. Allam MD, Al Azhar University, Cairo, Egypt; Bret Beheim PhD, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany; M. Linda Sutherland
In sedentary industrialized populations, men exhibit high testosterone in young adulthood compared to subsistence populations, and testosterone declines with age and adiposity. In late adulthood, low testosterone is associated with cardiovascular mortality. However, coronary risk factors like obesity impact both testosterone and cardiovascular outcomes. Here we assess the role of endogenous testosterone on coronary artery calcium in a subsistence population with relatively low testosterone level
ben.trumble@gmail.com
Alejandra Núñez-de la Mora
Faculty
cardiovascular disease, testosterone, obesity
Please post a videotape of my talk online if posting is possible
5
Imputation Efficacy Across Diverse Global Human Populations
8/15/2023
3:00pm
Non-western population health
Auditorium
Talk
0:15
Charleston Chiang
Jordan L. Cahoon, University of Southern California, Los Angeles, CA; Xinyue Rui, University of Southern California, Los Angeles, CA; Echo Tang, University of Southern California, Los Angeles, CA; Christopher Simons, University of Southern California, Los Angeles, CA; Jalen Langie, University of Southern California, Los Angeles, CA; Minhui Chen, University of Southern California, Los Angeles, CA; Ying-Chu Lo, University of Southern California, Los Angeles, CA; Charleston W. K. Chiang, University
Genotype imputation, now fundamental for genome-wide association studies, also contributes to the growing disparity in genetic studies due to the lack of diversity in imputation reference panels. Despite the increased number of admixed samples in state-of-the-art references, imputation for populations primarily residing outside of North America are expected to fall short in performance due to persisting underrepresentation. To illustrate this point, we curated data from 23 publications published
charleston.chiang@med.usc.edu
Alejandra Núñez-de la Mora
Faculty
diverse populations, genotype imputation, genetic epidemiology
Please post a videotape of my talk online if posting is possible
5
Pleiotropy complicates identifying adaptive phenotypes
8/15/2023
3:15pm
Non-western population health
Auditorium
Talk
0:15
Cynthia Beall
Sienna Craig, Dartmouth College, Hanover; Anna Di Rienzo, University of Chicago, Chicago; David Witonsky, University of Chicago, Chicago; James J Yu, University of California at San Diego, San Diego; Esteban Moya, University of California at San Diego, San Diego; Tatum Simonson, University of California at San Diego, San Diego; Frank Powell, University of California at San Diego, San Diego; Buddha Basnyat, Oxford Tropical Research Unit – Kathmandu, Kathmandu; Samar Farha, Cleveland Clinic, Cle
Two genes in the oxygen homeostasis pathway show strong signals of positive natural selection among Tibetan populations exposed to chronic hypoxia. EGLN1 encodes an oxygen sensor, and EPAS1 encodes a subunit of a transcription factor with hundreds of target genes. Here we test the hypothesis that these loci influence traits relevant to adaptation to high-altitude hypoxia. 417 ethnic Tibetan women, 46 – 86, residing at > 3500m in Nepal provided DNA and phenotypes. Candidate SNP analysis detect
cmb2@case.edu
Alejandra Núñez de la Mora
Faculty
high altitude, reproductive success, genetic adaptation, pleiotropy
Please post a videotape of my talk online if posting is possible
5
TUESDAY AFTERNOON COFFEE BREAK
8/15/2023
3:30pm
Coffee break 3
Atrium
Other
0:30
Coffee
The evolution of spectrum in antibiotics and bacteriocins
8/15/2023
4:00pm
Prize talk
Auditorium
Plenary talk
0:45
Jacob Palmer
Jacob Palmer, University of Oxford
A key property of many antibiotics is that they will kill or inhibit a diverse range of microbial species. This broad-spectrum of activity has its evolutionary roots in ecological competition, whereby bacteria and other microbes use antibiotics to suppress other strains and species. However, many bacteria also use narrow-spectrum toxins, such as bacteriocins, that principally target conspecifics. Why has such a diversity in spectrum evolved? In this talk, I will discuss evolutionary models we de
jacob.palmer@biology.ox.ac.uk
Cynthia Beall
Faculty
Antibiotics, bacteriocins
Gilbert S Omenn Prize
Experimental Evolution to Study the Evolution of Antibiotic Resistance
8/15/2023
4:45pm
Prize talk
Auditorium
Plenary talk
0:45
Alfonso Santos-Lopez
Alfonso Santos-Lopez; Melissa J Fritz, Department of Microbiology and Molecular Genetics, University of Pittsburgh, PA; Jeffrey B Lombardo, Department of Microbiology and Molecular Genetics, University of Pittsburgh, PA; Ansen HP Burr, Department of Microbiology and Molecular Genetics, University of Pittsburgh, PA; Victoria A Heinrich, Department of Microbiology and Molecular Genetics, University of Pittsburgh, PA; Christopher W Marshall, Department of Biological Sciences, Marquette University,
Antimicrobial resistance is one of the main challenges facing modern medicine. The emergence and rapid dissemination of resistant bacteria are decreasing the effectiveness of antibiotics in clinical use. The ability of a bacterial population to develop resistance to an antibiotic depends on various factors, including the availability of mutations that increase resistance, bacterial lifestyle, and the intensity of selection imposed by the compound, among others. Experimental evolution, combined w
alfonso.santos@csic.cnb.es
Cynthia Beall
Faculty
experimental evolution, antibiotic resistance
Please post a videotape of my talk online if posting is possible
George C Williams Prize
TUESDAY DINNER (on your own)
8/15/2023
7:30pm
Other location
Other
Dinner
Council dinner
8/15/2023
7:30pm
Other location
Other
Council dinner
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